According to new research published this week in American Heart Association Journal, Apple Watch can detect arrhythmias other than Atrial Fibrillation (AFib). The Apple watch irregular pulse detection algorithm was found to have a positive predictive value of 0.84 for the identification of atrial fibrillation (AFib). MyHealthyApple reports: The Apple Heart Study investigated a smartwatch-based irregular pulse notification algorithm to identify AFib. For this secondary analysis, the researchers analyzed participants who received an ambulatory ECG patch after index irregular pulse notification. Among 419,297 participants enrolled in the Apple Heart Study, 450 participant ECG patches were analyzed, with no AF on 297 ECG patches (66%). Non-AF arrhythmias (excluding supraventricular tachycardias [less than] 30 beats and pauses [less than] 3 seconds) were detected in 119 participants (40.1%) with ECG patches without AFib. 76 participants (30.5%) reported subsequent AF diagnoses. In participants with an irregular pulse notification on the Apple Watch and no AF observed on ECG patch, atrial and ventricular arrhythmias, mostly PACs and PVCs, were detected in 40% of participants.

GW Ori is a star system 1,300 light years from Earth in the constellation of Orion. It is surrounded by a huge disk of dust and gas, a common feature of young star systems that are forming planets. But fascinatingly, it is a system with not one star, but three. From a report: As if that were not intriguing enough, GW Ori's disk is split in two, almost like Saturn's rings if they had a massive gap in between. And to make it even more bizarre, the outer ring is tilted at about 38 degrees. Scientists have been trying to explain what is going on there. Some hypothesized that the gap in the disk could be the result of one or more planets forming in the system. If so, this would be the first known planet that orbits three stars at once, also known as a circumtriple planet.

Now the GW Ori system has been modeled in greater detail, and researchers say a planet -- a gassy world as massive as Jupiter -- is the best explanation for the gap in the dust cloud. Although the planet itself cannot be seen, astronomers may be witnessing it carve out its orbit in its first million years of its existence. A paper on the finding was published in September in the Monthly Notices of the Royal Astronomical Society. The scientists say it disproves an alternative explanation -- that the gravitational torque of the stars cleared the space in the disk. Their paper suggests there is not enough turbulence in the disk, known as its viscosity, for this explanation to suffice The finding also highlights how much more there is to learn about the unexpected ways in which planets can form.

Air pollution is likely to have been responsible for up to 6 million premature births and 3 million underweight babies worldwide every year, research shows. From a report: The analysis, which combines the results of multiple scientific studies, is the first to calculate the total global burden of outdoor and indoor air pollution combined. Indoor pollution, mostly from cooking stoves burning solid fuel such as coal or wood, made up almost two-thirds of the total pollution burden on pregnancies in 2019, according to the latest findings. This is especially true in developing areas, such as in some parts of south-east Asia and sub-Saharan Africa. "At an individual level, indoor air pollution exposure appears to carry a much higher burden compared to outdoor levels," said Rakesh Ghosh, an epidemiologist at University of California, San Francisco and lead researcher on the paper, published in the journal Plos Medicine.

"So, minimising household pollution exposure, to the extent possible, should be part of the message during prenatal care, especially where household pollution is prevalent." Air pollution is usually measured according to exposure to particulate matter smaller than 2.5 microns: once inhaled, the minuscule size of these particles allows them to be absorbed deep into the bloodstream, potentially causing far-reaching health problems.

To slow the speed at which high temperatures and warm waters bleach the corals of the Great Barrier Reef, Australian scientists are spraying droplets of ocean water into the sky to form clouds to protect the environmental treasure. From a report: Researchers working on the so-called Cloud Brightening project said they use a turbine to spray microscopic sea particles to thicken existing clouds and reduce sunlight on the world's largest coral reef ecosystem located off Australia's northeast coast. The water droplets evaporate leaving only tiny salt crystals which float up into the atmosphere allowing water vapour to condense around them, forming clouds, said Daniel Harrison, a senior lecturer at Southern Cross University, who runs the project.

"If we do it over an extended period of time for a few weeks to a couple of months when the corals are experiencing a marine heatwave we can actually start to lower the water temperature over the Reef," said Harrison. The project had its second trial in March, the end of the Southern Hemisphere summer when the Reef off Australia's northeast is at its hottest, gathering valuable data on the atmosphere when corals are at most risk of bleaching. A combination of light and warm water causes coral bleaching. By cutting light over the reef by 6% in summer, "bleaching stress" would be cut by 50% to 60% on the undersea ecosystem, Harrison said.

Mexico's scientific community has reacted with outrage after the country's chief prosecutor requested arrest warrants for 31 scientists, researchers and academics on accusations of organised crime, money laundering and embezzlement -- charges that could land them alongside drug cartel kingpins in one of the country's most notorious lockups. From a report: A judge at the maximum security Altiplano prison -- from which Joaquin "El Chapo" Guzman escaped in 2015 -- denied granting the arrest warrants on Wednesday. But the federal prosecutor immediately announced plans to pursue arrest warrants for the third time. The university professors have been accused of violating a law that prevents members of an advisory board from receiving money from a government science fund. But that law was passed in 2019, and the scientists got the $2.5m years earlier when it was apparently legal. Those involved have denied the funds were illegal or misused. The National Council on Science and Technology (Conacyt) has described the reaction to the arrest warrant applications as "a concerted wave of disinformation," which was spreading "terror" in the scientific community.

Samsung has proposed a way to build brain-like computer chips by "copying and pasting" a brain's neuron wiring map onto 3D neuromorphic chips. Engadget reports: The approach would rely on a nanoelectrode array that enters a large volumes of neurons to record both where the neurons connect and the strength of those connections. You could copy that data and 'paste' it to a 3D network of solid-state memory, whether it's off-the-shelf flash storage or cutting-edge memory like resistive RAM. Each memory unit would have a conductance that reflects the strength of each neuron connection in the map. The result would be an effective return to "reverse engineering the brain" like scientists originally wanted, Samsung said.

The move could serve as a 'shortcut' to artificial intelligence systems that behave like real brains, including the flexibility to learn new concepts and adapt to changing conditions. You might even see fully autonomous machines with true cognition, according to the researchers.
"Envisioned by the leading engineers and scholars from Samsung and Harvard University, the insight was published as a Perspective paper, titled 'Neuromorphic electronics based on copying and pasting the brain'..." Samsung said in a statement.

In short, they're proposing a method that "directly downloads the brain's neuronal connection map onto the memory chip."

schwit1 shared this report from LiveScience: The world's longest known cave system just set a new record after surveyors spent hours mapping an additional 8 miles (13 kilometers) of the passageways at Mammoth Cave National Park in Kentucky.

The corridors at Mammoth Cave now measure a whopping 420 miles (676 km) in length, according to the National Park Service (NPS). That's about the distance between New York City and Raleigh, North Carolina.

Mapping the cave system was a huge undertaking, carried out by volunteers at the Cave Research Foundation (CRF), a Kentucky-based nonprofit group, and other locals, including those from the Central Kentucky Karst Coalition. "Many of the cave trips are long and arduous, involving climbing, vertical exposure, squeezes, crawlways, water and mud," Karen Willmes, the eastern operations manager with CRF, said in an NPS statement... "After the trip, cartographers turn the data collected on the cave trip into a map. Other volunteers provide surface support.

Slashdot reader StellarThoughts shares an announcement from the University of California, Riverside. (Alternate URL): Plants have the ability to perceive drought. When they do, they emit a hormone that helps them hold on to water. This same hormone, ABA, sends a message to seeds that it isn't a good time to germinate, leading to lower crop yields and less food in places where it's hot — an increasingly long list as a result of climate change.

"If you block ABA, you mess with the chemical pathway that plants use to prevent seed germination," said Aditya Vaidya, UC Riverside project scientist and study author. "Our new chemical, Antabactin, does exactly this. If we apply it, we have shown that dormant seeds will sprout."

Demonstrations of Antabactin's effectiveness are described in a new paper published in the Proceedings of the National Academy of Sciences. This work builds on the same team's creation of a chemical that mimics the effects of the ABA hormone, produced by plants in response to drought stress. That chemical, Opabactin, slows a plant's growth so it conserves water and doesn't wilt. It works by inducing plants to close tiny pores in their leaves and stems, which prevents water from escaping. Next, the team wanted to find a molecule that would have the opposite effect, opening the pores, encouraging germination and increasing plant growth. Though seed dormancy has largely been removed through breeding, it is still a problem in some crops like lettuce. Sean Cutler, a UC Riverside plant cell biology professor and study co-author, said accelerating and slowing plant growth are important tools for farmers. "Our research is all about managing both of these needs," he said...

In their paper, the team members showed that applying Antabactin to barley and tomato seeds accelerated germination. Conceivably, both Antabactin and Opabactin could work together to help crops flourish in a world becoming drier and hotter. Once Antabactin has helped seeds sprout into healthy plants, a farmer might start saving water early in the growing season by spraying Opabactin. This way, enough water is "banked" for when the plants start flowering.

"An international team of physicists have come up with a way to generate antimatter in the lab," reports Popular Mechanics, theoretically "allowing them to recreate conditions that are similar to those near a neutron star." This setup, at Helmholtz-Zentrum Dresden-Rossendorf (HZDR) research laboratory in Germany, involves two high-intensity laser beams that can generate a jet of antimatter, as outlined in a paper published earlier this summer in the journal Communications Physics. That could make antimatter-based research far more accessible for scientists around the world...

it's tremendously difficult to recreate a neutron star's extreme conditions in terms of the science and logistics — imagine if a sugar cube weighed as much as Mount Everest in your laboratory! Two, scientists want to make antimatter for further analysis in the lab... So how did the researchers at Helmholtz-Zentrum Dresden-Rossendorf figure out how to generate antimatter? They're using opposing lasers in a setup they're referring to as a laser pincer... There's a tiny piece of plastic that both lasers shoot toward. As the lasers destroy the plastic, they send clouds of electrons toward each other... By smashing particles together between two lasers, scientists can begin to approach the intensely concentrated gravity and matter of a neutron star...

In this case, scientists are still speculating that the laser pincers will work, with support from a computer simulation that has helped them test and confirm their theory. Now, the next step is to begin building the rig that will really fire the lasers. "[C]olleagues are developing a platform that can be used to experimentally test whether the magnetic fields actually form as our simulations predict," HZDR physicist Toma Toncian says.
Thanks to Slashdot reader Third Position for submitting the article!

On Monday RockDoctor (Slashdot reader #15,477) wrote: Regular readers may remember recurring concerns over the instability of the island of La Palma, in the Canaries archipelago [population: 85,000]. Estimates of the threat ranged from 100 megadeaths (from tsunami impacts on the coasts of about a dozen countries bordering the Atlantic — including the eastern seaboard of America) down to a 10- to 30- metre tsunami with a few thousand deaths in the Canaries and other Atlantic islands (Madeira, Azores).

To bring relaxation and good cheer, today we have the news that the volcano at the centre of these concerns is erupting for the first time in 50 years. While a hundred or so houses have so far been destroyed and around 5000 people evacuated from the path of the lava flow, some people are more sanguine — Spain's Tourism Minister considers the eruption a "great attraction", and indeed recent eruptions in Hawaii did see a significant amount of "Volcano tourism". To be honest, I'm rather tempted myself — Etna studiously did not erupt during my last holiday there. Or should I wait for Vesuvius to go off again?
Here's an update. "Seven days after a volcano on La Palma erupted, lava flow and ash continue to spread shutting down the local airport and leaving hundreds without a home," according to one newspaper report (with several photos of the aftermath). "As of Friday, almost 6,000 people have evacuated.

"The government is working to locate emergency housing for the affected families as researchers are unsure when the ash and lava flow will stop."

Meanwhile, the Associated Press reports, "scientists said another volcanic vent opened up, exposing islanders to possible new dangers." The intensity of the eruption that began Sept. 19 has increased in recent days, prompting the evacuation of three additional villages on the island, part of Spain's Canary Islands archipelago in the Atlantic Ocean off northwest Africa...

Emergency crews pulled back from the volcano Friday as explosions sent molten rock and ash over a wide area...

AltMachine shares a report from Phys.Org: Chinese scientists recently reported a de novo route for artificial starch synthesis from carbon dioxide (CO2) for the first time. Relevant results were published in Science on Sept. 24. The new route makes it possible to produce starch, a major component of grains, by industrial manufacturing instead of traditional agricultural planting and opens up a new technical route for synthesizing complex molecules from CO2. The artificial route can produce starch from CO2 with an efficiency 8.5-fold higher than starch biosynthesis in maize, suggesting a big step towards going beyond nature. It provides a new scientific basis for creating biological systems with unprecedented functions. "If the overall cost of the process can be reduced to a level economically comparable with agricultural planting in the future, it is expected to save more than 90% of cultivated land and freshwater resources," said MA Yanhe, corresponding author of the study. In addition, it would also help to avoid the negative environmental impact of using pesticides and fertilizers, improve human food security, facilitate a carbon-neutral bioeconomy, and eventually promote the formation of a sustainable bio-based society.

schwit1 shares a report from TMZ: The 90-year-old actor is slated to be part of the second crew to take the space flight in the New Shepard capsule. That would make him the oldest person ever to be launched into space. We're told Shatner will be on board in October for the 15-minute civilian flight -- similar to the last launch. What we don't know -- BUT WHAT WOULD BE AWESOME -- is if he wears his Capt. Kirk getup. Our sources say the mission will be filmed for a documentary. We're told Shatner's people were talking to Discovery about the special, but that didn't materialize ... but our sources say Shatner and Co. have taken the project elsewhere and are in negotiations.

Engineers at the University of Cincinnati are developing new ways to convert greenhouse gases to fuel to address climate change and get astronauts home from Mars. UC: UC College of Engineering and Applied Science assistant professor Jingjie Wu and his students used a carbon catalyst in a reactor to convert carbon dioxide into methane. Known as the "Sabatier reaction" from the late French chemist Paul Sabatier, it's a process the International Space Station uses to scrub the carbon dioxide from air the astronauts breathe and generate rocket fuel to keep the station in high orbit. But Wu is thinking much bigger.

The Martian atmosphere is composed almost entirely of carbon dioxide. Astronauts could save half the fuel they need for a return trip home by making what they need on the red planet once they arrive, Wu said. "It's like a gas station on Mars. You could easily pump carbon dioxide through this reactor and produce methane for a rocket," Wu said. UC's study was published in the journal Nature Communications with collaborators from Rice University, Shanghai University and East China University of Science and Technology. Wu began his career in chemical engineering by studying fuel cells for electric vehicles but began looking at carbon dioxide conversion in his chemical engineering lab about 10 years ago.

"I realized that greenhouse gases were going to be a big issue in society," Wu said. "A lot of countries realized that carbon dioxide is a big issue for the sustainable development of our society. That's why I think we need to achieve carbon neutrality." The Biden Administration has set a goal of achieving a 50% reduction in greenhouse gas pollutants by 2030 and an economy that relies on renewable energy by 2050. "That means we'll have to recycle carbon dioxide," Wu said. Wu and his students, including lead author and UC doctoral candidate Tianyu Zhang, are experimenting with different catalysts such as graphene quantum dots -- layers of carbon just nanometers big -- that can increase the yield of methane.

Searches for Covid-19 tests on Google are surging as the delta variant spreads in the U.S. and more employers and large-scale events require testing. From a report: The number of Americans looking up "at-home Covid test near me" on the platform has doubled in the past month, according to Google Trends, while those asking how long rapid test results take is up by 250%. In the past week, users were also more interested in searches related to tests, rather than vaccines, in most states, with Louisiana and Mississippi as exceptions. The highly contagious delta variant has kept cases high in the U.S. This is creating the need for more tests as children return to school, workplaces resume activities and consumers head back to concerts and events. This appears to have taken manufacturers by surprise after months of flagging demand. The Biden administration also recently announced plans to require either vaccination or weekly testing for companies with 100 or more employees. That comes on top of the federal-worker mandate.

Thousands of scientific studies had to toss out weeks of data because of a 56-second TikTok video by a teenager. From a report: The July 23rd video is short and simple. It opens with recent Florida high school graduate and self-described "teen author" Sarah Frank sitting in her bedroom and smiling at the camera. "Welcome to side hustles I recommend trying -- part one," she says in the video, pointing users to the website Prolific.co. "Basically, it's a bunch of surveys for different amounts of money and different amounts of time." That video got 4.1 million views in the month after it was posted and sent tens of thousands of new users flooding to the Prolific platform. Prolific, a tool for scientists conducting behavioral research, had no screening tools in place to make sure that it delivered representative population samples to each study. Suddenly, scientists used to getting a wide mix of subjects for their Prolific studies saw their surveys flooded with responses from young women around Frank's age.

Though not particularly well known, Prolific is part of a small collection of online tools that have transformed the way corporations and scientists study the way people think and act. The first and largest of these research platforms is Amazon-owned Mechanical Turk, which was released in 2005 as a general-purpose platform for crowdsourcing work on repetitive tasks. Soon after it was released, behavioral scientists realized its potential value for their research, and it quickly revolutionized several research fields. [...] The Behavioral Lab at Stanford mainly uses the newer, smaller Prolific platform for online studies these days, said Nicholas Hall, director of the Behavioral Lab at the Stanford School of Business. While many Mechanical Turk customers are big businesses conducting corporate research, Prolific gears its product to scientists.

The smaller platform offers more transparency, promises to treat survey participants more ethically, and promises higher-quality research subjects than alternative platforms like Mechanical Turk. Scientists doing this sort of research in the United States generally want a pool of subjects who speak English as a first language, are not too practiced at taking psychological surveys, and together make up a reasonably representative demographic sample of the American population. Prolific, most agreed, did a good job providing high-quality subjects. The sudden change in the platform's demographics threatened to upend that reputation. In the days and weeks after Frank posted her video, researchers scrambled to figure out what was happening to their studies. A member of the Stanford Behavioral Laboratory posted on a Prolific forum, "we have noticed a huge leap in the number of participants on the platform in the US Pool, from 40k to 80k. Which is great, however, now a lot of our studies have a gender skew where maybe 85% of participants are women. Plus the age has been averaging around 21."

An anonymous reader quotes a report from Ars Technica: Engineers at Columbia University [...] figured out how to simultaneously 3D-print and cook layers of pureed chicken, according to a recent paper published in the journal npj Science of Food. [...] The scientists purchased raw chicken breast from a local convenience store and then pureed it in a food processor to get a smooth, uniform consistency. They removed any tendons and refrigerated the samples before repackaging them into 3D-printing syringe barrels to avoid clogging. The cooking apparatus used a high-powered diode laser, a set of mirror galvanometers (devices that detect electrical current by deflecting light beams), a fixture for custom 3D printing, laser shielding, and a removable tray on which to cook the 3D-printed chicken.

"During initial laser cooking, our laser diode was mounted in the 3D-printed fixture, but as the experiments progressed, we transitioned to a setup where the laser was vertically mounted to the head of the extrusion mechanism," the authors wrote. "This setup allowed us to print and cook ingredients on the same machine." They also experimented with cooking the printed chicken after sealing it in plastic packaging. The results? The laser-cooked chicken retained twice as much moisture as conventionally cooked chicken, and it shrank half as much while still retaining similar flavors. But different types of lasers produced different results. The blue laser proved ideal for cooking the chicken internally, beneath the surface, while the infrared lasers were better at surface-level browning and broiling. As for the chicken in plastic packaging, the blue laser did achieve slight browning, but the near-infrared laser was more efficient at browning the chicken through the packaging. The team was even able to brown the surface of the packaged chicken in a pattern reminiscent of grill marks.

"Millimeter-scale precision allows printing and cooking a burger that has a level of done-ness varying from rare to well-done in a lace, checkerboard, gradient, or other custom pattern," the authors wrote. "Heat from a laser can also cook and brown foods within a sealed package... [which] could significantly increase their shelf life by reducing their microbial contamination, and has great commercial applications for packaged to-go meals at the grocery store, for example." To make sure the 3D-printed chicken still appealed to the human palate, the team served samples of both 3D-printed laser cooked and conventionally cooked chicken to two taste testers. It's not a significant sample size, but both taste testers preferred the laser-cooked chicken over the conventionally cooked chicken, mostly because it was less dry and rubbery and had a more pleasing texture. One tester was even able to identify which sample was the laser-cooked chicken and did note a slight metallic taste from the laser heating.

Scientists have successfully used artificial intelligence to create a new drug regime for children with a deadly form of brain cancer that has not seen survival rates improve for more than half a century. The Guardian reports: The breakthrough, revealed in the journal Cancer Discovery, is set to usher in an "exciting" new era where AI can be harnessed to invent and develop new treatments for all types of cancer, experts say. Computer scientists and cancer specialists at the ICR and the Royal Marsden NHS Foundation Trust used AI to work out that combining the drug everolimus with another called vandetanib could treat diffuse intrinsic pontine glioma (DIPG), a rare and fast-growing type of brain tumor in children. Currently, DIPG and other similar types of tumors are incredibly difficult to remove surgically from children because they are diffuse, which means they do not have well-defined borders suitable for operations. But after crunching data on existing drugs, the team found everolimus could enhance vandetanib's capacity to "sneak" through the blood-brain barrier and treat the cancer.

The combination has proved effective in mice and has now been tested in children. Experts now hope to test it on a much larger group of children in major clinical trials. The research found that combining the two drugs extended survival in mice by 14% compared with those receiving a standard control treatment. Both the drugs in the research, which was funded by Brain Research UK, the DIPG Collaborative, Children with Cancer UK and the Royal Marsden Cancer Charity, among others, are already approved to treat other types of cancer. "The AI system suggested using a combination of two existing drugs to treat some children with DIPG -- one to target the ACVR1 mutation, and the other to sneak the first past the blood brain barrier," said Chris Jones, professor of paediatric brain tumor biology at the ICR. "The treatment extended survival when we tested it in a mouse model, and we have already started testing it out in a small number of children. We still need a full-scale clinical trial to assess whether the treatment can benefit children, but we've moved to this stage much more quickly than would ever have been possible without the help of AI."

Impossible Foods' latest meatless product is set to hit tables from Thursday: plant-based pork that claims to be tastier and healthier than the real deal. CNBC reports: The ground pork product will first be available in restaurants in the U.S., Hong Kong and Singapore, with further plans for retail expansion in those markets in the coming months. It marks the California-based company's third commercial launch after ground beef and chicken nuggets as it seeks to solidify its position in the growing plant-based protein space.

Speaking in a first-on interview ahead of the launch, Impossible Foods' president Dennis Woodside told CNBC's "Squawk Box Asia" that the pork alternative could beat the real deal in both taste and nutritional value. "Pig typically isn't regarded as a healthy product, but here you have a substitute that tastes just as good but is actually better for you," he said. According to the company, the product -- which is made primarily from soy -- provides the same amount of protein as its traditional meat counterpart, but with no cholesterol, one-third less saturated fat, and far fewer calories. Meantime, in a recent blind taste test conducted by Impossible Foods, it found that the majority (54%) of Hong Kong consumers said they preferred the meatless pork product.

A key Centers for Disease Control and Prevention advisory group unanimously voted Thursday to recommend distributing Pfizer and BioNTech's Covid-19 booster shots to older Americans and nursing home residents, clearing the way for the agency to give the final OK as early as this evening. CNBC reports: The agency's Advisory Committee on Immunization Practices specifically endorsed giving third Pfizer shots to people 65 and older in the first of four votes. The panel will also vote on whether to recommend the shots for adults with medical conditions that put them at risk of severe disease and those who are more frequently exposed to the virus -- possibly including people in nursing homes and prisons, teachers, front-line health employees and other essential workers. The elderly were among the first groups to get the initial shots in December and January.

The vote is seen as mostly a win for President Joe Biden, whose administration has said it wants to give booster shots to all eligible Americans 16 and older as early as this week. While the CDC panel's recommendation doesn't give the Biden administration everything it wanted, boosters will still be on the way for millions of Americans. The endorsement comes a day after the Food and Drug Administration granted emergency use authorization to administer third Pfizer shots to many Americans six months after they complete their first two doses. While the CDC's panel's recommendation isn't binding, Director Dr. Rochelle Walensky is expected to accept the panel's endorsement shortly.

ytene writes: As reported by CNBC, the US Court of Federal Claims has released a redacted version of the lawsuit, filed by Jeff Bezos' Blue Origin, in a complaint against NASA. Earlier this year, the agency had awarded a $2.9 billion contract to SpaceX for the design and development of a lunar lander.

Although NASA has a long history of awarding contracts to promote innovation and competition, the Blue Origin suit seemed a little unusual given the company's current lack of launch experience (they have completed numerous successful tests, including a high-altitude "edge of space" flight for Bezos, his brother and guests, but have yet to place any vehicle in orbit, let alone establish a credible, commercial space flight presence).

As was also reported by CNBC, the Government Accountability Office conducted an investigation in to the initial Blue Origin complaint, after NASA suspended the process, but found no evidence that NASA awarded the contract incorrectly and denied the initial Blue Origin complaint.