Space

SpaceX Mars Prototype Rocket Nails Landing For the First Time, But Explodes On Pad (cnn.com) 129

A SpaceX rocket prototype, known as SN10, soared over South Texas during test flight Wednesday before swooping down to a pinpoint landing near its launch site. Approximately three minutes after landing, however, multiple independent video feeds showed the rocket exploding on its landing pad. CNN reports: SpaceX's SN10, an early prototype of the company's Starship Mars rocket, took off around 5:15 pm CT and climbed about six miles over the coastal landscape, mimicking two previous test flights SpaceX has conducted that ended in an explosive crash. Wednesday marked the first successful landing for a Starship prototype. "We've had a successful soft touch down on the landing pad," SpaceX engineer John Insprucker said during a livestream of the event. "That's capping a beautiful test flight of Starship 10." It was unclear what caused the rocket to explode after landing, and the SpaceX livestream cut out before the conflagration.

He added that SpaceX has several other prototypes already in production and the next, SN11, will be ready to roll out for another test flight 'in the near future." SpaceX's first launch attempt on Wednesday, around 3 pm CT, was aborted at the last tenth of a second. SpaceX CEO Elon Musk said in a tweet that the abort was triggered by pre-set standards around the rocket's thrust, which Musk described as "slightly conservative." He added that the company would increase the rocket's thrust limit, giving the rocket more wiggle room for getting a go-ahead for liftoff. The company then recycled the SN10's fuel ahead of the second, successful attempt.

Science

Cephalopod Passes Cognitive Test Designed For Human Children (sciencealert.com) 63

mi shares a report from ScienceAlert: The marshmallow test, or Stanford marshmallow experiment, is pretty straightforward. A child is placed in a room with a marshmallow. They are told, if they can manage not to eat the marshmallow for 15 minutes, they'll get a second marshmallow, and be allowed to eat both. This ability to delay gratification demonstrates cognitive abilities such as future planning, and it was originally conducted to study how human cognition develops; specifically, at what age a human is smart enough to delay gratification if it means a better outcome later.

Because it's so simple, it can be adjusted for animals. Obviously you can't tell an animal they'll get a better reward if they wait, but you can train them to understand that better food is coming if they don't eat the food in front of them straight away. [...] The researchers found that all of the cuttlefish in the test condition decided to wait for their preferred food (the live shrimp), but didn't bother to do so in the control group, where they couldn't access it. "Cuttlefish in the present study were all able to wait for the better reward and tolerated delays for up to 50-130 seconds, which is comparable to what we see in large-brained vertebrates such as chimpanzees, crows and parrots," the researchers said.

The other part of the experiment was to test how good the six cuttlefish were at learning. They were shown two different visual cues, a grey square and a white one. When they approached one, the other would be removed from the tank; if they made the "correct" choice, they would be rewarded with a snack. Once they had learnt to associate a square with a reward, the researchers switched the cues, so that the other square now became the reward cue. Interestingly, the cuttlefish that learnt to adapt to this change the quickest were also the cuttlefish that were able to wait longer for the shrimp reward.
The team's research has been published in Proceedings of the Royal Society B.
NASA

NASA's Perseverance Rover Sends Stunning Images of Mars (bbc.com) 37

Since landing on Mars on February 18, NASA's Perseverance rover has sent back some amazing images from around its landing site, Jezero Crater, a 30-mile wide impact depression just north of the Red Planet's equator. BBC shares a selection of the pictures sent from the mission, "as Perseverance hunts for signs of past microbial life, seeks to characterize the planet's geology and past climate, and collects Martian rock." You can view the images here.
Japan

Japan Billionaire Seeks 'Crew' For Moon Trip (reuters.com) 44

Japanese billionaire Yusaku Maezawa on Wednesday launched a search for eight people to join him as the first private passenger on a trip around the moon with Elon Musk's SpaceX. He had originally planned to invite artists for the weeklong voyage slated for 2023. Reuters reports: The rejigged project will "give more people from around the globe the chance to join this journey. If you see yourself as an artist, then you are an artist," Maezawa said. The first stage of the application process runs to March 14. The entrepreneur, who sold his online fashion business Zozo Inc to SoftBank in 2019, is paying the entire cost of the voyage on SpaceX's next-generation reusable launch vehicle, dubbed the Starship.
Medicine

CVS, Walgreens Look For Big Data Reward From Covid-19 Vaccinations (wsj.com) 33

Thelasko shares a report from The Wall Street Journal: Administering Covid-19 vaccines comes with a valuable perk for retail pharmacies: access to troves of consumer data. Chains such as CVS Health Corp., Walmart Inc. and Walgreens-Boots Alliance, Inc. are collecting data from millions of customers as they sign up for shots, enrolling them in patient systems and having recipients register customer profiles.

The retailers say they are using the information to promote their stores and services, tailor marketing and keep in touch with consumers. The companies also say the information is critical in streamlining vaccinations and improving record-keeping, while ensuring only qualified people are receiving shots.

Biotech

Beyond Meat Signs Global Supply Deals With McDonald's, KFC and Pizza Hut (agfundernews.com) 109

U.S. plant-based protein company Beyond Meat has signed global supply deals with fast food firms McDonald's and Yum! Brands, which includes KFC, Pizza Hut, Taco Bell and others. AgFunderNews reports: The three-year strategic agreement with McDonald's will see Beyond Meat become the 'preferred supplier' of patties for the fast food chain's new McPlant plant-based burger. Under their separate strategic partnership, Beyond Meat and Yum! Brands will co-develop a range of exclusive plant-based protein menu items for the latter's KFC, Pizza Hut, and Taco Bell chains.

Bruce Friedrich, executive director of the Good Food Institute, said in comments sent to AFN that the two deals represent "the clearest sign yet that the future of meat will be plant-based." "The world's largest restaurant chains are placing plant-based meat directly on the plates of millions of customers around the world," he said. "With more restaurants and revenue than any other food chains on the planet, McDonald's and Yum! Brands will bring plant-based meat onto the mainstream menus of millions of people. When these restaurant chains move, the entire food industry takes notice."

Science

New Technique Reveals Centuries of Secrets in Locked Letters (nytimes.com) 36

M.I.T. researchers have devised a virtual-reality technique that lets them read old letters that were mailed not in envelopes but in the writing paper itself after being folded into elaborate enclosures. From a report: In 1587, hours before her beheading, Mary, Queen of Scots, sent a letter to her brother-in-law Henry III, King of France. But she didn't just sign it and send it off. She folded the paper repeatedly, cut out a piece of the page and left it dangling. She used that strand of paper to sew the letter tight with locking stitches. In an era before sealed envelopes, this technique, now called letterlocking, was as important for deterring snoops as encryption is to your email inbox today. Although this art form faded in the 1830s with the advent of mass-produced envelopes, it has recently attracted renewed attention from scholars. But they have faced a problem: How do you look at the contents of such locked letters without permanently damaging priceless bits of history?

On Tuesday, a team of 11 scientists and scholars at the Massachusetts Institute of Technology and other institutions disclosed their development of a virtual-reality technique that lets them perform this delicate task without tearing up the contents of historical archives. In the journal Nature Communications, the team tells of virtually opening four undelivered letters written from 1680 and 1706. The dispatches had ended up in a wooden postal trunk in The Hague. Known as the Brienne Collection, the box contains 3,148 items, including 577 letters that were never unlocked. The new technique could open a window into the long history of communications security. And by unlocking private intimacies, it could aid researchers studying stories concealed in fragile pages found in archives all over the world.

Space

Rocket Lab Reveals Plans For Reusable Rocket With 8 Ton Payload (engadget.com) 52

Rocket Lab has unveiled plans for a larger rocket that can carry bigger payloads than its current reusable trooper, the Electron. It's called the Neutron and will be capable of carrying 8 metric tons to low-Earth orbit compared to the Electron's 660 lbs capacity. Engadget reports: The Neutron will also have a fully reusable first stage that can land on an ocean platform, in the same vein as SpaceX's Falcon 9 booster. Rocket Lab is looking to fast-track the rocket's first flight to 2024 by using the existing launch pad at Virginia's Mid-Atlantic Regional Spaceport located at the NASA Wallops Flight Facility. It's also scouting sites across the US to build a new factory where the Neutron will be assembled at scale.

The new rocket is designed with an eye to the future of mega-satellite constellations. Its larger payload means it can take multiple small satellites in batches to specific orbital planes, creating a "a more targeted approach to building out" the massive projects, said Peter Beck, Rocket Lab founder and CEO. Demand for the constellations is growing, with the satellite networks enabling better navigation and providing communications in rural areas back here on Earth. The Neutron's lift capacity also means it should be able to transport 98 percent of all satellites forecast to launch through 2029.

Science

Asteroid Dust Found in Crater Closes Case of Dinosaur Extinction (phys.org) 56

Phys.org shares an announcement from the University of Texas at Austin: Researchers believe they have closed the case of what killed the dinosaurs, definitively linking their extinction with an asteroid that slammed into Earth 66 million years ago by finding a key piece of evidence: asteroid dust inside the impact crater.

Death by asteroid rather than by a series of volcanic eruptions or some other global calamity has been the leading hypothesis since the 1980s, when scientists found asteroid dust in the geologic layer that marks the extinction of the dinosaurs. This discovery painted an apocalyptic picture of dust from the vaporized asteroid and rocks from impact circling the planet, blocking out the sun and bringing about mass death through a dark, sustained global winter — all before drifting back to Earth to form the layer enriched in asteroid material that's visible today. In the 1990s, the connection was strengthened with the discovery of a 125-mile-wide Chicxulub impact crater beneath the Gulf of Mexico that is the same age as the rock layer.

The new study seals the deal, researchers said, by finding asteroid dust with a matching chemical fingerprint within that crater at the precise geological location that marks the time of the extinction... The telltale sign of asteroid dust is the element iridium — which is rare in the Earth's crust, but present at elevated levels in certain types of asteroids... In the crater, the sediment layer deposited in the days to years after the strike is so thick that scientists were able to precisely date the dust to a mere two decades after impact.

"We are now at the level of coincidence that geologically doesn't happen without causation," said co-author Sean Gulick, a research professor at the UT Jackson School of Geosciences who co-led the 2016 expedition with Joanna Morgan of Imperial College London...

The dust is all that remains of the 7-mile-wide asteroid that slammed into the planet millions of years ago, triggering the extinction of 75% of life on Earth, including all nonavian dinosaurs.

Space

The Dream of Sending a Submarine Through the Methane Seas of Saturn's Moon Titan (nytimes.com) 51

"Mars, Shmars; this voyager is looking forward to a submarine ride under the icebergs on Saturn's strange moon," says the New York Times, introducing a piece by cosmic affairs correspondent Dennis Overbye: What could be more exciting than flying a helicopter over the deserts of Mars? How about playing Captain Nemo on Saturn's large, foggy moon Titan — plumbing the depths of a methane ocean, dodging hydrocarbon icebergs and exploring an ancient, frigid shoreline of organic goo a billion miles from the sun? Those are the visions that danced through my head recently...diverted to the farther reaches of the solar system by the news that Kraken Mare, an ocean of methane on Titan, had recently been gauged for depth and probably went at least 1,000 feet down. That is as deep as nuclear submarines will admit to going. The news rekindled my dreams of what I think would be the most romantic of space missions: a voyage on, and ultimately even under, the oceans of Titan...

NASA recently announced that it would launch a drone called Dragonfly to the Saturnian moon in 2026. Proposals have also circulated for an orbiter, a floating probe that could splash down in a lake, even a robotic submarine. "The Titan submarine is still going," said Dr. Valerio Poggiali, research associate at the Cornell Center for Astrophysics and Planetary Science, in an email — although it is unlikely to happen before Titan's next summer, around 2047. By then, he said, there will be more ambient light and the submarine conceivably could communicate on a direct line to Earth with no need of an orbiting radio relay.

Titan is the weirdest place in the solar system, in some regards, and also the world most like our own. Like Earth, it has a thick atmosphere of mostly nitrogen (the only moon that has much of an atmosphere at all), and like Earth, it has weather, rain, rivers and seas. But on this world, when it rains, it rains gasoline. Hydrocarbon material drifts down like snow and is shaped into dunes by nitrogen winds. Rivers have carved canyons through mountains of frozen soot, and layers of ice float on subsurface oceans of ammonia. The prevailing surface temperature is minus 290 degrees Fahrenheit. A chemical sludge that optimistic astronomers call "prebiotic" creeps along under an oppressive brown sky. Besides Earth, Titan is the only world in the universe that is known to harbor liquid on its surface — with everything that could imply.

Medicine

America Authorizes Johnson & Johnson's COVID-19 Vaccine For Emergency Use (bbc.com) 118

America's Food and Drug Administration just authorized Johnson & Johnson's COVID-19 vaccine for emergency use, according to CBS News. "The vaccine is the third to be approved for use in the United States, and the first that requires only one shot..." Among people who got the vaccine in clinical trials, there were no COVID-related deaths. Phase 3 clinical trials also showed protection against multiple emerging virus variants, including a more contagious strain that was first discovered in South Africa and has since been detected in the U.S.

The vaccine can be stored at standard refrigerator temperatures for up to three months.

More from the BBC: The company has agreed to provide the U.S. with 100 million doses by the end of June. The first doses could be available to the US public as early as next week. The U.K., EU and Canada have also ordered doses, and 500 million doses have also been ordered through the Covax scheme to supply poorer nations.
Mars

The Perseverance Rover CPU Has Similar Specs To a Clamshell Ibook From 2001 (baesystems.com) 109

An anonymous reader writes: NASA's Perseverence rover, which is currently exploring Mars, has as it's CPU a BAE Systems RAD 750 running at a 200 Mhz and featuring 256 Megabytes of RAM with 2 Gigabytes of storage. This is a radiation hardened version of the PowerPC G3, with specs roughly equivalent to the Clamshell Ibook that Reese Witherspoon used in Legally Blond back in 2001. This follows a tradition of old tech on space rovers — the Sojourner rover which explored Mars in 1997 used an Intel 80C85 running at 2 Mhz, similar to what could have been found in the classic Radio Shack TRS-80 model 100 portable from 1983.
In a comment on the original submission, long-time Slashdot reader Mal-2 argues "There's not as much distance between the actual capabilities of a CPU now and twenty years ago as there would be if you made the same comparison a decade ago." In the last 12 years or so, the CPUs have gotten more efficient and cooler-running (thus suitable for portable devices) to a much greater degree than they've actually gained new functionality. Retro computing is either going to stay stuck in the 1990s, or it's not going to be very interesting in the future.
Mars

The Mars Perseverance Rover's Parachute Contained a Secret Message (apnews.com) 14

"The huge parachute used by NASA's Perseverance rover to land on Mars contained a secret message," reports the Associated Press — thanks to the rover's puzzle-loving systems engineer Ian Clark.

"During a live stream discussing the landing, one Nasa commentator said: 'Sometimes we leave messages in our work for others to find. So we invite you all to give it a shot and show your work,'" reports the Guardian.

One Reddit user actually deciphered the message using Python code.

Long-time Slashdot reader rufey writes that "Decoded the slogan is 'Dare Mighty Things' — a line from President Theodore Roosevelt — which is a mantra at JPL and adorns many of the center's walls." The orange sections of the 70-foot (21-meter) parachute represented ones in binary code, while the yellow sections represented zeroes. (So the letter "A" becomes yellow-yellow-yellow-yellow-yellow-yellow-orange...) The Associated Press reports: Clark also included the GPS coordinates for the mission's headquarters at the Jet Propulsion Laboratory in Pasadena, California. Clark, a crossword hobbyist, came up with the idea two years ago. Engineers wanted an unusual pattern in the nylon fabric to know how the parachute was oriented during descent. Turning it into a secret message was "super fun," he said Tuesday. Only about six people knew about the encoded message before Thursday's landing, according to Clark. They waited until the parachute images came back before putting out a teaser during a televised news conference Monday...

Another added touch not widely known until touchdown: Perseverance bears a plaque depicting all five of NASA's Mars rovers in increasing size over the years — similar to the family car decals seen on Earth.

Deputy project manager Matt Wallace promises more so-called hidden Easter eggs...

The official Twitter feed for the rover has already revealed that it's carrying another message hidden in a plaque with a logo of the sun — "Explore as One," written in Morse code.

Some other interesting facts about the rover:
Math

Quantum Computer Solves Decades-Old Problem Three Million Times Faster Than a Classical Computer (zdnet.com) 77

ZDNet reports: Scientists from quantum computing company D-Wave have demonstrated that, using a method called quantum annealing, they could simulate some materials up to three million times faster than it would take with corresponding classical methods.

Together with researchers from Google, the scientists set out to measure the speed of simulation in one of D-Wave's quantum annealing processors, and found that performance increased with both simulation size and problem difficulty, to reach a million-fold speedup over what could be achieved with a classical CPU... The calculation that D-Wave and Google's teams tackled is a real-world problem; in fact, it has already been resolved by the 2016 winners of the Nobel Prize in Physics, Vadim Berezinskii, J. Michael Kosterlitz and David Thouless, who studied the behavior of so-called "exotic magnetism", which occurs in quantum magnetic systems....

Instead of proving quantum supremacy, which happens when a quantum computer runs a calculation that is impossible to resolve with classical means, D-Wave's latest research demonstrates that the company's quantum annealing processors can lead to a computational performance advantage... "What we see is a huge benefit in absolute terms," said Andrew King, director of performance research at D-Wave. "This simulation is a real problem that scientists have already attacked using the algorithms we compared against, marking a significant milestone and an important foundation for future development. This wouldn't have been possible today without D-Wave's lower noise processor."

Equally as significant as the performance milestone, said D-Wave's team, is the fact that the quantum annealing processors were used to run a practical application, instead of a proof-of-concept or an engineered, synthetic problem with little real-world relevance. Until now, quantum methods have mostly been leveraged to prove that the technology has the potential to solve practical problems, and is yet to make tangible marks in the real world.

Looking ahead to the future, long-time Slashdot reader schwit1 asks, "Is this is bad news for encryption that depends on brute-force calculations being prohibitively difficult?"
Science

Stanford Researchers Identify Four Causes For 'Zoom Fatigue' and Their Simple Fixes (stanford.edu) 74

In the first peer-reviewed article that systematically deconstructs Zoom fatigue from a psychological perspective, published in the journal Technology, Mind and Behavior on Feb. 23, Professor Jeremy Bailenson, founding director of the Stanford Virtual Human Interaction Lab (VHIL), has taken the medium apart and assessed Zoom on its individual technical aspects. He has identified four consequences of prolonged video chats that he says contribute to the feeling commonly known as "Zoom fatigue." Below are four primary reasons why video chats fatigue humans, according to the study: 1. Excessive amounts of close-up eye contact is highly intense.
2. Seeing yourself during video chats constantly in real-time is fatiguing.
3. Video chats dramatically reduce our usual mobility.
4. The cognitive load is much higher in video chats.
The article also offers solutions to alleviate the fatigues.
Earth

Plastic Bottles Holding 2.3 Litres Are Least Harmful To the Planet (newscientist.com) 184

Using plastic bottles that contain the most liquid for the lowest packaging weight could help reduce plastic waste. From a report: Plastic pollution is a huge problem for the world, with much plastic waste reaching the oceans where it can affect marine life. In recognition of this, many researchers are developing strategies to tackle the plastic waste problem. Now, Rafael Becerril-Arreola at the University of South Carolina and his colleagues have come up with a relatively simple method to make a difference: change the packaging size to maximise its capacity for a given weight of plastic. "We realised we could establish a relationship between supermarket beverage sales and plastic waste," says Becerril-Arreola. "I saw the opportunity to create an impact, and I took it."

Becerril-Arreola and his team focused on polyethylene terephthalate (PET), the most common material in plastic bottles. They weighed 187 empty bottles of different sizes from bestselling drink brands to determine the weight of plastic required to produce a bottle of a given capacity. They also compared this against PET waste and drink sales in Minnesota between 2009 and 2013, as the state government there reliably collects waste statistics and its bottled drink consumption is close to the US national average. The researchers found that the most efficient bottles -- those with the greatest capacity relative to the weight of plastic used to make the bottle -- had a volume between 0.5 and 2.9 litres. Bottles of this size are typically bought for on-the-go use or social gatherings. Bottles that were smaller (under 0.4 litres) or larger (over 3 litres) used more plastic in relation to each bottle's capacity.

Medicine

Vaccines Adapted for Variants Will Not Need Lengthy Testing, FDA Says (nytimes.com) 103

The Food and Drug Administration said this week that vaccine developers would not need to conduct lengthy randomized controlled trials for vaccines that have been adapted to protect against concerning coronavirus variants. From a report: The recommendations, which call for small trials more like those required for annual flu vaccines, would greatly accelerate the review process at a time when scientists are increasingly anxious about how the variants might slow or reverse progress made against the virus. The guidance was part of a slate of new documents the agency released on Monday, including others addressing how antibody treatments and diagnostic tests might need to be retooled to respond to the virus variants. Together, they amounted to the federal government's most detailed acknowledgment of the threat the variants pose to existing vaccines, treatments and tests for the coronavirus, and came weeks after the F.D.A.'s acting commissioner, Dr. Janet Woodcock, said the agency was developing a plan.

"The emergence of the virus variants raises new concerns about the performance of these products," Dr. Woodcock said in a statement Monday. "We want the American public to know that we are using every tool in our toolbox to fight this pandemic, including pivoting as the virus adapts." Most of the vaccine manufacturers with authorized vaccines or candidates in late-stage trials have already announced plans to adjust their products to address the vaccine variants. The Moderna and Pfizer-BioNTech vaccines use mRNA technology that the companies have said can be used to alter the existing vaccines within six weeks, although testing and manufacturing would take longer. Moderna has already begun developing a new version of its vaccine that could be used as a booster shot against a virus variant that originated in South Africa, known as B.1.351, which seems to dampen the effectiveness of the existing vaccines. A fast-spreading coronavirus variant first observed in Britain has also gained a worrisome mutation that could make it harder to control with vaccines. That variant with the mutation was found in the United States last week.

Medicine

Does Private Equity Investment in Healthcare Benefit Patients? Evidence from Nursing Homes (nber.org) 243

The summary of a study by National Bureau of Economic Research: The past two decades have seen a rapid increase in Private Equity (PE) investment in healthcare, a sector in which intensive government subsidy and market frictions could lead high-powered for-profit incentives to be misaligned with the social goal of affordable, quality care. This paper studies [PDF] the effects of PE ownership on patient welfare at nursing homes. With administrative patient-level data, we use a within-facility differences-in-differences design to address non-random targeting of facilities. We use an instrumental variables strategy to control for the selection of patients into nursing homes.

Our estimates show that PE ownership increases the short-term mortality of Medicare patients by 10%, implying 20,150 lives lost due to PE ownership over our twelve-year sample period. This is accompanied by declines in other measures of patient well-being, such as lower mobility, while taxpayer spending per patient episode increases by 11%. We observe operational changes that help to explain these effects, including declines in nursing staff and compliance with standards. Finally, we document a systematic shift in operating costs post-acquisition toward non-patient care items such as monitoring fees, interest, and lease payments.

Mars

NASA's Mars Perseverance Rover Provides Front-Row Seat to Landing, First Audio Recording of Red Planet (nasa.gov) 56

New video from NASA's Mars 2020 Perseverance rover chronicles major milestones during the final minutes of its entry, descent, and landing (EDL) on the Red Planet on Feb. 18 as the spacecraft plummeted, parachuted, and rocketed toward the surface of Mars. A microphone on the rover also has provided the first audio recording of sounds from Mars. From a report: From the moment of parachute inflation, the camera system covers the entirety of the descent process, showing some of the rover's intense ride to Mars' Jezero Crater. The footage from high-definition cameras aboard the spacecraft starts 7 miles (11 kilometers) above the surface, showing the supersonic deployment of the most massive parachute ever sent to another world, and ends with the rover's touchdown in the crater. A microphone attached to the rover did not collect usable data during the descent, but the commercial off-the-shelf device survived the highly dynamic descent to the surface and obtained sounds from Jezero Crater on Feb. 20. About 10 seconds into the 60-second recording, a Martian breeze is audible for a few seconds, as are mechanical sounds of the rover operating on the surface. "For those who wonder how you land on Mars -- or why it is so difficult -- or how cool it would be to do so -- you need look no further," said acting NASA Administrator Steve Jurczyk. "Perseverance is just getting started, and already has provided some of the most iconic visuals in space exploration history. It reinforces the remarkable level of engineering and precision that is required to build and fly a vehicle to the Red Planet."
Science

Ghana Scientist Tries Gene Editing To Create Healthier Sweet Potatoes (cornell.edu) 61

The Cornell Alliance for Science seeks to build "a significant international alliance of partners" to "correct misinformation and counter conspiracy theories" slowing progress on climate change, synthetic biology, agricultural innovations, and other issues.

Slashdot reader wooloohoo shares their article about research on Ghana's first gene-edited crop — a high-yielding sweet potato with increased beta carotone content. "For sweet potatoes, we want to look at how we can use the CRISPR-Cas9 system to increase beta carotene," said Samuel Acheampong of the University of Cape Coast's Department of Molecular Biology and Biotechnology, who has been working on the project for the past year. "Beta carotene is a big deal for us because as animals, when we eat beta carotene, our cells are able to convert them into vitamin A."

The World Health Organization estimates that between 250,000 and 500,000 children in developing nations go blind every year as a result of vitamin A deficiency, making it the world's leading preventable cause of childhood blindness. Some 50 percent of them die within a year of losing their sight. Respiratory illnesses and infectious and diarrheal diseases in children also have been linked to vitamin A deficiency. Acheampong is using CRISPR-Cas9 to knock out the genes responsible for the production of an enzyme in the sweet potato that converts beta carotene into other products. This will leave higher beta carotene content in the crop, which when consumed by humans will allow them to produce vitamin A. Sweet potato is a very popular vegetable in Ghana, making it ideal for a biofortification effort of this kind...

Additionally, Acheampong is researching how to increase the size of the crop's storage roots. "I'm looking at a set of genes which affects the transport of sugars in plants. So I'm trying to use the CRISPR genome editing to knock out some sets of genes so that there will be more flow of sugars in the crop, which will definitely lead to increase in the yield...."

He estimates it will take him up to five years to complete his research before any conversation can begin around putting the product in the hands of farmers. "Getting it to the market may take a long time, depending on regulations, etc.," he said.

In another article, The Alliance for Science cites a researcher with the Chinese Academy of Sciences in Beijing who argues "it is unlikely that genome editing-based next generation breeding will completely displace conventional approaches; only when combined with other technologies, such as high-throughput phenotyping, genomic selection and speed breeding, can we guarantee the widespread implementation of genome editing in agriculture."

"This multidisciplinary approach will advance plant breeding to help secure a second Green Revolution in order to meet the increasing food demands of a rapidly growing global population under ever-changing climate conditions."

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