Security

Anti-Vaxxer Hijacks QR Codes At COVID-19 Check-In Sites (threatpost.com) 117

schwit1 shares a report from Threatpost: Quick-response (QR) codes used by a COVID-19 contact-tracing program were hijacked by a man who simply slapped up scam QR codes on top to redirect users to an anti-vaccination website, according to local police. He now faces two counts of "obstructing operations carried out relative to COVID-19 under the Emergency Management Act," the South Australia Police said in a statement announcing the arrest. His arrest may just be a drop in the bucket: Reports of other anti-vax campaigners doing the same thing abound. Law enforcement added an additional warning to would-be QR code scammers: "Any person found to be tampering or obstructing with business QR codes will likely face arrest and court penalty of up to $10,000." The police said no personal data was breached, but the incident highlights that truly all an attacker needs is a printer and a pack of Avery labels to do real damage.

In this case, the QR codes were being used by the South Australian government's official CovidSafe app to access a device's camera, scan the code and collect real-time location data to be used for contact tracing in case of a COVID-19 outbreak, ABC News Australia reported. That's a lot of personal data linked to a single QR code just waiting to be stolen. "In this instance, people who scanned the illegitimate QR code were redirected to a website distributing misinformation from the anti-vaxxer community," Bill Harrod, vice president of public sector at Ivanti, told Threatpost. "While this is concerning, the outcome could have been far more perilous."

Space

Jeff Bezos' Blue Origin Will Soon Begin Selling Tickets For Rides On Its Space Tourism Rocket (cnbc.com) 70

Today, Blue Origin revealed that it will be selling the first tickets for rides on its space tourism rocket called New Shepard. According to CNBC, the first ticket (or tickets?) will go on sale starting next week, on Wednesday, May 5. From the report: Blue Origin did not reveal how much tickets will cost, only saying that more details will come on May 5 to those who submit their name and email on a form on the company's website. "Sign up to learn how you can buy the very first seat on New Shepard," according to the company's website. The announcement's video features Bezos going out to the capsule of New Shepard after the company's test flight earlier this month. It shows him driving across the Texas desert, the remote location of the New Shepard launch facility -- notably at the wheel of a Rivian R1T electric truck, which is emblazoned with Blue Origin's signature feather.

New Shepard is designed to carrying as many as six people at a time on a ride past the edge of space, with the capsules on previous test flights reaching an altitude of more than 340,000 feet (or more than 100 km). The capsule, which has massive windows to give passengers a view, spends as much as 10 minutes in zero gravity before returning to Earth. The rocket launches vertically, with the booster detaching and returning to land at a concrete pad nearby. The capsule's return is slowed down by a set of parachutes, before softly landing in the desert.

Medicine

High-Bandwidth Wireless BCI Demonstrated In Humans For First Time (arstechnica.com) 60

An anonymous reader quotes a report from Ars Technica: Coming on the heels of the Neuralink announcement earlier this month -- complete with video showing a monkey playing Pong with its mind, thanks to a wireless brain implant -- researchers with the BrainGate Consortium have successfully demonstrated a high-bandwidth wireless brain-computer interface (BCI) in two tetraplegic human subjects. The researchers described their work in a recent paper published in the journal IEEE Transactions in Biomedical Engineering. As for the latest Neuralink breakthrough, Ars Science Editor John Timmer wrote last week that most of the individual pieces of Neuralink's feat have been done before -- in some cases, a decade before (BrainGate is among those earlier pioneers). But the company has taken two important steps toward its realization of a commercial BCI: miniaturizing the device and getting it to communicate wirelessly, which is harder than it sounds.

According to [John Simeral of Brown University, a member of the BrainGate consortium and lead author of the new paper], the BrainGate wireless system makes the opposite tradeoff -- higher bandwidth and fidelity -- because it wants all the finer details of the data for its ongoing research. In that regard, it complements the Utrecht and Neuralink systems in the BCI space. The new BrainGate system is based on the so-called Brown Wireless Device (BWD) designed by Arto Nurmikko, and it replaces the cables with a small transmitter that weighs about 1.5 ounces. The transmitter sits atop the user's head and connects wirelessly to an implant electrode array inside the motor cortex.

There were two participants in the clinical trial -- a 35-year-old man and a 65-year-old man -- both of whom were paralyzed by spinal cord injuries. They were able to continuously use the BCI for a full 24 hours, even as they slept, yielding continuous data over that time period. (The medical-grade battery lasts for 36 hours.) "We can learn more about the neural signals that way because we can record over long periods of time," said Simeral. "And we can also begin to learn a little bit about how people actually will use the system, given the freedom to do so." His team was encouraged by the fact that one of its study participants often asked if they could leave the wireless transmitters on a little longer. He has a head tracker he can use as a fallback, but several nights a week, he would choose to use the wireless BrainGate system because he liked it.
"Right now, we typically decode or interpret the spiking activity from networks of neurons," said Simeral. "There are other encoding mechanisms that have been studied in the brain that have to do with how the oscillations in the brain are related to these spiking signals. There's information in the different oscillation frequencies that might relate to, for example, sleep state, attention state, other phenomenon that we care about. Without a continuous recording, you've surrendered the ability to learn about any of those. Learning how this all happens in the human brain in the home as people are behaving and having different thoughts requires having a broadband system recording from the human brain."

"The ability to potentially have individuals with disability using these systems at home on demand, I think is a great step forward," said Simeral. "More broadly, going forward, having more players in the field, having more funding, is important. I see nothing but great things from all of these interactions. For our own work, we see things on the horizon that were impossible five years ago, when there was essentially nobody in the corporate world interested in this space. So I think it's a very promising time."
Medicine

Pfizer and Moderna Vaccines Are 94% Effective Against COVID-19 Hospitalization In Older Adults, Says CDC (thehill.com) 60

According to a new study from the CDC, Pfizer and Moderna vaccines were 94 percent effective in preventing hospitalization for COVID-19 among people age 65 and older. The Hill reports: The study provides new evidence on the benefits of vaccination, and builds on results from the clinical trials by adding real-world evidence from 417 hospitalized adults in 14 states from January to March. "This multisite U.S. evaluation under real-world conditions suggests that vaccination provided protection against COVID-19-associated hospitalization among adults aged [65 and older]," the study states.

The 94 percent efficacy rate was for people who were fully vaccinated, meaning they were at least two weeks past their second dose. For people who were only partially vaccinated, meaning they were more than two weeks past the first dose but less than two weeks past the second dose, effectiveness was 64 percent. Notably, no significant effectiveness was found for people who were less than 14 days past their first dose, highlighting that it takes some time for protection to kick in and that people should not disregard precautions right away. The results show that as vaccinations spread, hospitalizations and deaths are set to decline, the CDC said.

Space

'Forgotten Astronaut' Michael Collins Dies (npr.org) 46

An astronaut who flew on one of the most famous space missions of all time has died. From a report: Michael Collins, 90, was part of the three-member crew on Apollo 11, the first lunar landing mission in 1969. Unlike Neil Armstrong and Buzz Aldrin, he never walked on the moon. Collins stayed behind and piloted the command module as it circled above. Because of that, Collins is often called the 'forgotten astronaut'. Collins had been battling cancer. In a statement released by his family, "He spent his final days peacefully, with his family by his side. Mike always faced the challenges of life with grace and humility, and faced this, his final challenge in the same way."

NASA Administrator Steve Jurczyk said the nation lost a true pioneer, "NASA mourns the loss of this accomplished pilot and astronaut, a friend of all who seek to push the envelope of human potential. Whether his work was behind the scenes or on full view, his legacy will always be as one of the leaders who took America's first steps into the cosmos. And his spirit will go with us as we venture toward farther horizons." When Neil Armstrong first stepped on the moon and uttered the famous phrase, "Houston, Tranquility Base here, the Eagle has landed," Collins was in orbit, 60 miles above, just as busy, and just as excited, telling the team back in Houston he was listening to communications with his comrades, and it was "fantastic." Aldrin and Armstrong were on the lunar surface just under 22 hours. The world was transfixed. Seeing them bunny-hop along, take pictures and collect lunar samples during their single, short moonwalk. All the while, Collins circled the moon. Looking down at the barren lunar landscape and peering back at the Earth. "The thing I remember most is the view of planet Earth from a great distance," he said later. "Tiny. Very shiny. Blue and white. Bright. Beautiful. Serene and fragile."

Earth

Rare Chunks of Earth's Mantle Found Exposed In Maryland 53

Maya Wei-Haas writes via National Geographic: Standing among patches of muddy snow on the outskirts of Baltimore, Maryland, I bent down to pick up a piece of the planet that should have been hidden miles below my feet. On that chilly February day, I was out with a pair of geologists to see an exposed section of Earth's mantle. While this layer of rock is usually found between the planet's crust and core, a segment peeks out of the scrubby Maryland forest, offering scientists a rare chance to study Earth's innards up close. Even more intriguing, the rock's unusual chemical makeup suggests that this piece of mantle, along with chunks of lower crust scattered around Baltimore, was once part of the seafloor of a now-vanished ocean.

Over the roughly 490 million years since their formation, these hunks of Earth were smashed by shifting tectonic plates and broiled by searing hot fluids rushing through cracks, altering both their composition and sheen. Mantle rock is generally full of sparkly green crystals of the mineral olivine, but the rock in my hand was surprisingly unremarkable to look at: mottled yellow-brown stone occasionally flecked with black. Because of this geologic clobbering, scientists have struggled for more than a century to determine the precise origins of this series of rocks. Now, Guice and his colleagues have applied a fresh eye and state-of-the-art chemical analyses to the set of rocky exposures in Baltimore. Their work shows that the seemingly bland series of stones once lurked underneath the ancient Iapetus Ocean.

More than half a billion years ago, this ocean spanned some 3,000 to 5,000 miles, cutting through what is now the United States' eastern seaboard. Much of the land where the Appalachian mountains now stand was on one side of the ocean, and parts of the modern East Coast were on the other. "It's a huge ocean between them, and we've got a little bit of that ocean smooshed in Baltimore," says Guice, lead author of a recent study describing the find in the journal Geosphere.
Books

Popular Science Is Now a Fully Digital Magazine (popsci.com) 20

kackle writes: I just received an email telling me that "Popular Science" magazine is no more. That is, it is to be delivered to readers from now on only via ones and zeros. I can't say I had a subscription since its beginnings in 1872, but I did learn much from the rag and will sincerely miss it. "Today, we're unveiling our biggest change in my tenure: Popular Science is now a fully digital magazine," writes Editor-in-Chief Corinne Iozzio. In addition to "redesigned" and "reimagined stories" made especially for mobile devices, Iozzio notes that their various apps "include an archive of 15-plus years of back issues..."

"The mediums may change, but even after all these evolutions and iterations, our core belief remains as fixed and focused as it was in 1872: Embracing science and tech means living in the realm of possibility."
Earth

Lockdowns Cut South Asia Smog. They Could Fill Reservoirs, Too. (nytimes.com) 13

Cleaner skies over South Asia that resulted from pandemic lockdowns last year likely affected the timing of snowmelt in the Indus River basin of Pakistan and India, researchers reported on Monday. From a report: The lockdowns cut emissions of soot and other pollutants, as people drove less and the generation of electricity, largely from coal, was reduced. That meant less soot was deposited on snow, where it absorbs sunlight, emits heat and causes faster melting. The cleaner snow in 2020 reflected more sunlight and did not melt as fast, the researchers said. In all, that delayed runoff into the Indus River of more than than one and a half cubic miles of melt water, they calculated, similar to the volume of some of the largest reservoirs in the United States. More than 300 million people depend on the Indus for water, much of which starts as snow in the high peaks of the Karakoram and other mountain ranges.

Timing of melt water runoff in the spring and summer can be crucial for managing water supplies over time. In many parts of the world, climate change has affected this timing, with warmer temperatures and a shift to more rain and less snow causing more snow to melt sooner. Slower runoff can thus be beneficial, helping managers of reservoirs store more water and maintain a steady flow over the year. Ned Bair, a snow hydrologist at the University of California, Santa Barbara, and the lead researcher, said that while they could not prove conclusively that the pandemic was the reason for the timing delay, "it seems unlikely that anything else would have led to that." India imposed a nationwide lockdown in late March last year that continued through early May. Several studies showed rapid improvements in air quality in that period, particularly in and around Delhi, which is notorious for having some of the most unhealthy air in the world.

Medicine

CDC Says Vaccinated Americans Don't Need a Mask Outdoors in Small Groups (cnet.com) 282

Americans who have been fully vaccinated against COVID-19 can safely do many outdoor activities without wearing a mask, according to updated guidance Tuesday from the US Centers for Disease Control and Prevention. However, health officials said vaccinated people should continue to wear a mask indoors and at crowded outdoor events, such as concerts, parades and sports events. From a report: "There are many situations where fully vaccinated people do not need to wear a mask, particularly if they are outdoors," said CDC Director Dr. Rochelle Walensky during a press briefing. "If you are fully vaccinated and want to attend a small outdoor gathering with people who are vaccinated and unvaccinated or dine at an outdoor restaurant with friends form multiple households, the science shows -- if you're vaccinated -- you can do so safely unmasked."

The CDC released a graphic to help people make decisions about when to wear a mask both outdoors and indoors. For fully vaccinated people, the CDC says these outdoor activities are safe without a mask: Walk, run or bike outdoors with members of your household. Attend a small, outdoor gathering with fully vaccinated family and friends. Attend a small, outdoor gathering with fully vaccinated and unvaccinated people. Dine at an outdoor restaurant with friends from multiple households.

NASA

Bezos' Blue Origin Protests NASA Awarding Astronaut Lunar Lander Contract To Musk's SpaceX (cnbc.com) 162

"Jeff Bezos' Blue Origin filed a protest with the Government Accountability Office against NASA on Monday, challenging the space agency's award of a nearly $3 billion moon lander contract to Elon Musk's SpaceX earlier this month," reports CNBC. In response, Musk teased on Twitter that Bezos couldn't "get it up (to orbit)." From the report: SpaceX, in a competition against Blue Origin and Leidos' subsidiary Dynetics, was awarded $2.89 billion for NASA's Human Landing System program. The HLS program is focused on building a lunar lander that can carry astronauts to the moon's surface under NASA's Artemis missions. For HLS, SpaceX bid a variation of its Starship rocket, prototypes of which the company has been testing at its facility in Texas. NASA was previously expected to choose two of the three teams to competitively build lunar landers, making the sole selection of SpaceX a surprise given the agency's prior goals for the program to continue to be a competition.

Blue Origin decried the award as "flawed" in a statement to CNBC, saying that NASA "moved the goalposts at the last minute." "In NASA's own words, it has made a 'high risk' selection. Their decision eliminates opportunities for competition, significantly narrows the supply base, and not only delays, but also endangers America's return to the Moon. Because of that, we've filed a protest with the GAO," Blue Origin said. Blue Origin revealed that NASA evaluated the company's HLS proposal to cost $5.99 billion, or roughly twice that of SpaceX. The company argued in its protest filing that NASA's cost for funding both proposals would have been under $9 billion -- or near how much the agency spent for SpaceX and Boeing to develop competing astronaut capsules under the Commercial Crew program.

First, Bezos' company said NASA did not give SpaceX's competitors an opportunity to "meaningfully compete" after "the agency's requirements changed due to its undisclosed, perceived shortfall of funding" for the HLS program. Second and third, Blue Origin said that NASA's acquisition was flawed under the agency's acquisition rules and its evaluation of the company's proposal "unreasonable." Fourth, the company asserted that NASA "improperly and disparately" evaluated SpaceX's proposal. And finally, Blue Origin said that NASA's evaluation of the proposals changed the weight it gave to key criteria, making price "the most important factor because of perceived funding limitations."

Medicine

Millions Are Skipping Their Second Doses of Covid Vaccines (nytimes.com) 247

Millions of Americans are not getting the second doses of their Covid-19 vaccines, and their ranks are growing. From a report: More than five million people, or nearly 8 percent of those who got a first shot of the Pfizer or Moderna vaccines, have missed their second doses, according to the most recent data from the Centers for Disease Control and Prevention. That is more than double the rate among people who got inoculated in the first several weeks of the nationwide vaccine campaign. Even as the country wrestles with the problem of millions of people who are wary about getting vaccinated at all, local health authorities are confronting an emerging challenge of ensuring that those who do get inoculated are doing so fully. The reasons vary for why people are missing their second shots. In interviews, some said they feared the side effects, which can include flulike symptoms. Others said they felt that they were sufficiently protected with a single shot.

Those attitudes were expected, but another hurdle has been surprisingly prevalent. A number of vaccine providers have canceled second-dose appointments because they ran out of supply or didn't have the right brand in stock. Walgreens, one of the biggest vaccine providers, sent some people who got a first shot of the Pfizer or Moderna vaccine to get their second doses at pharmacies that only had the other vaccine on hand. Several Walgreens customers said in interviews that they scrambled, in some cases with help from pharmacy staff, to find somewhere to get the correct second dose. Others, presumably, simply gave up. From the outset, public health experts worried that it would be difficult to get everyone to return for a second shot three or four weeks after the first dose. It is no surprise that, as vaccines are rolled out more broadly, the numbers of those skipping their second dose have gone up.

Medicine

Biden Admin Will Share Millions of AstraZeneca Vaccine Doses Worldwide (politico.com) 149

An anonymous reader quotes a report from Politico: The Biden administration is preparing to send up to 60 million AstraZeneca doses to countries in need over the next several months, once a federal safety review is conducted, according to two senior Biden administration officials. The company has produced about 10 million doses of the vaccine for the U.S. but the FDA has not yet authorized their use. The agency is still examining the doses to ensure they meet the necessary quality control standards. An additional 50 million doses are in production, one of the senior officials said.

It is unclear where the U.S. will send the AstraZeneca doses and whether it will send them through COVAX or directly to individual countries. The administration's decision to commit the doses was first reported by the Associated Press. It comes on the heels of the Biden administration's announcement that it will send India raw materials and components to manufacture Covishield, a version of the AstraZeneca vaccine produced by the country's Serum Institute. Those materials were already wrapped up in contracts held by the U.S. But the administration decided over the weekend to divert pending orders of vaccine supplies such as filters to India, and to ship additional drugs, test kits and personal protective equipment. The administration has not yet decided whether to send India AstraZeneca doses directly.

China

China's 2024 Moon Probe Will Carry European Equipment (businessinsider.com) 19

Hmmmmmm writes: China plans to launch its next robot lunar lander in 2024, and it will carry equipment manufactured by scientists from France, Sweden, Italy, and Russia, Hu Hao, the program's chief designer, told the Xinhua News Agency on Saturday. The country aims to position the lander, named Chang'e 6, near the lunar south pole where it will collect samples, per the official Xinhua News Agency.

The Chang'e 6 lander is part of China's ongoing mission to successfully return moon samples back home "for comprehensive analysis and research," Hu said at a conference, Associated Press reported.

For the 2024 mission, The China National Space Administration has invited scientists from around the world to take part in the program, offering to transport solicited payloads into space. So far, four payloads designed by the international scientists have been preliminarily chosen, the Xinhua News Agency reported.

Mars

NASA's Ingenuity Mars Helicopter Successfully Flies Faster, Farther on Third Flight (nasa.gov) 29

"NASA's Ingenuity Mars Helicopter continues to set records, flying faster and farther on Sunday, April 25, 2021 than in any tests it went through on Earth," reports NASA: The helicopter took off at 1:31 a.m. EDT (4:31 a.m. PDT), or 12:33 p.m. local Mars time, rising 16 feet (5 meters) — the same altitude as its second flight. Then it zipped downrange 164 feet (50 meters), almost half the length of a football field, reaching a top speed of 6.6 feet per second (2 meters per second). [Roughly 4.5 miles an hour.]

After data came back from Mars starting at 10:16 a.m. EDT (7:16 a.m. PDT), Ingenuity's team at NASA's Jet Propulsion Laboratory in Southern California was ecstatic to see the helicopter soaring out of view. They're already digging through a trove of information gathered during this third flight that will inform not just additional Ingenuity flights but possible Mars rotorcraft in the future. "Today's flight was what we planned for, and yet it was nothing short of amazing," said Dave Lavery, the project's program executive for Ingenuity Mars Helicopter at NASA Headquarters in Washington. "With this flight, we are demonstrating critical capabilities that will enable the addition of an aerial dimension to future Mars missions."

NASA's chief pilot for the Mars helicopter calls this flight a big step "in which Ingenuity will begin to experience freedom in the sky," according to CNN.

From the sky Ingenuity snapped a photo of its own shadow on Mars, and earlier sent back the very first aerial color image — taken 17 feet (5.2-metre) above the surface of Mars by Ingenuity's high-resolution color camera with a 4208-by-3120-pixel sensor.
Medicine

Children from Parents Exposed to Chernobyl Nuclear Disaster Show No Genetic Damage (usnews.com) 80

HealthDay reports: There's no evidence of genetic damage in the children of parents who were exposed to radiation from the 1986 Chernobyl Nuclear Power Plant disaster in Ukraine, researchers say.

Several previous studies have examined the risks across generations of radiation exposure from events such as this, but have yielded inconclusive results. In this study, the investigators analyzed the genomes of 130 children and parents from families where one or both parents were exposed to radiation due to the Chernobyl accident, and where children were conceived afterward and born between 1987 and 2002.

There was no increase in gene changes in reproductive cells of study participants, and rates of new germline mutations were similar to those in the general population, according to a team led by Meredith Yeager of the U.S. National Cancer Institute, in Rockville, Md.

Businesses

Is SpaceX's Starlink Becoming the World's Dominant ISP? (cringely.com) 162

Technology/space pundit Robert Cringely writes that SpaceX's winning bid on NASA's Artemis lunar lander contract was helped by its flexibility in how it would be paid — made possibly by SpaceX's cushy financial position.

But he believes that's part of a larger story about SpaceX's "steadily crushing its competitors by building a hyper-efficient space ecosystem where the other guys are just building rockets," arguing that SpaceX has already won the global war of ISPs "at a net cost of ZERO dollars," if not a negative net cost, while realizing a dream of a satellite internet service that for 30 years has eluded investors like Bill Gates:

SpaceX making a profit where one would not normally exist comes thanks to U.S. residents who pay telephone and Internet bills. The U.S. Federal Communications Commission (FCC) has been socking-away for a decade about $1.8 billion per year from you and me, saving-up to pay for expansions of rural telephony and broadband. There is now about $16 billion in this federal kitty and the FCC is starting to spend it with telephone and internet service providers, paying them to extend broadband and voice services to remote rural users who are presently underserved or unserved completely. All of this is both perfectly legal and even a good idea. Everybody wins. But circumstances are turning out to indicate that SpaceX is probably winning more than anyone else... So far SpaceX has won auctions for service in parts of 35 states for a total of $885 million... SpaceX just bid for potential customers in places where other companies typically didn't even bother to bid. They took the obvious remote customers and apparently won't be over-charging them or the government, either...

There is no FCC rule saying Comcast couldn't sub-contract...difficult customers to Starlink... Instead of earning $885 million of those FCC subsidies, Starlink is more likely to gain half of the full $9.2 billion — money that can be used for any purpose including financing that Artemis lander. But remember that satellites are a global resource. If SpaceX launches 4000 or 12,000 Starlink satellites to serve the USA, they'll also serve anywhere else the satellites overfly, even North Korea. The same level of service Starlink offers in Omaha will be available in Vietnam or on tankers in the Pacific ocean.

Once Starlink becomes effectively the dominant ISP in America, it will also become the dominant ISP in the world. And all at no cost to SpaceX since the expansion will have been financed from our phone bills.

Cringely cites estimates that 40,000 satellites would be enough to serve every Internet user on Earth, as well as IoT devices and even future as-yet-uninvented network services.

He also asks whether this might ultimately make it harder for China to censor the internet — and whether Apple might attempt a competing satellite-to-phone network, possibly using technology from Samsung.
ISS

Astronauts Successfully Delivered to the International Space Station by SpaceX (cnn.com) 35

NASA has tweeted a video showing the arrival of four astronauts from three countries on the International Space Station early Satuday morning.

CNN describes the significance to their arrival — and what the astronauts will do during their six-month stay in space: This mission, dubbed Crew-2, marks the third-ever crewed flight for Elon Musk's company and the first to make use of a previously flown, privately-owned rocket booster and spacecraft... On Saturday morning, the capsule slowly aligned itself and moved in to dock directly with one of the space station's ports.

The crew consists of NASA astronauts Shane Kimbrough and Megan McArthur, Thomas Pesquet of the European Space Agency, and Akihiko Hoshide with Japan's JAXA space agency.

A prime focus of the astronauts' mission will be research with "tissue chips," or "small models of human organs containing multiple cell types that behave much the same as they do in the body" and that NASA hopes will advance the development of drugs and vaccines, according to the space agency. That work will build on years of studying biological and other scientific phenomena aboard the ISS, where the microgravity environment can give scientists a better fundamental understanding of how something works.

Kimbrough, McArthur, Pesquet, and Hoshide joined seven astronauts already on board the station, four of whom arrived on a different SpaceX Crew Dragon capsule in November. That brings the space station's current total of personnel to 11 — one of the largest crews the ISS has ever hosted. But that number will quickly drop back down to seven when four of the astronauts who'd been on board hitch a ride home from the station on April 28.

Medicine

The Most Effective Malaria Vaccine Yet Discovered (sciencemag.org) 30

An anonymous reader shares an excerpt from a Science Magazine blog, written by Derek Lowe: Excellent news today: we have word of the most effective malaria vaccine yet discovered. A year-long trial in Burkina Faso has shown 77% efficacy, which is by far the record, and which opens the way to potentially relieving a nearly incalculable burden of disease and human suffering.

This new vaccine (R21) uses a circumsporozoite protein (CSP) antigen -- that's a highly conserved protein of the parasite, involved in several functions as the parasite makes the move from mosquito to human and into different human tissues such as the salivary glands. This has been a vaccine ingredient before, such as in the RTS,S vaccine (the first one ever licensed), but R21 has a much higher proportion of CSP assembled into a virus-like particle. It also uses the exact same adjuvant from Novavax (Matrix-M) that they are using in their coronavirus vaccine -- you can't keep a good adjuvant down, and this Chilean-soapbark-based one seems to really kick the immune system up under all circumstances.

The higher-adjuvant cohort showed 77% vaccine efficacy, and the lower-adjuvant one showed 74% with (as you'd expect) overlapping confidence intervals. The first group had significantly higher antibody levels, though, and they're currently doing an additional year of follow-up to see how long the protection lasts and if these doses differentiate themselves. The antibody levels at the one-year mark in both groups were significantly higher than with the RTS,S vaccine, and in particular, antibodies against the repeat section in the middle of the circumsporozite protein seemed to correlate strongly with protection. No safety problems so far. The team is now planning a larger Phase III at five different African site, with varying seasonality and malaria loads.

Medicine

CDC Panel Recommends Using J&J COVID-19 Vaccine Without Restrictions, Saying Benefits Outweigh Risks (cnbc.com) 105

A Centers for Disease Control and Prevention advisory panel on Friday recommended the U.S. resume using the Johnson and Johnson Covid-19 vaccine, saying the benefits outweighed the risk. CNBC reports: The recommendation, which was adopted 10-4 with one abstention, by the CDC's Advisory Committee on Immunization Practices, will pave the way for U.S. regulators to lift their recommended pause on using the J&J shot as early as this weekend. The committee, an outside panel of experts that advises the CDC, decided to postpone a decision on the vaccine last week while officials continued to investigate cases of six women, ages 18 to 48, who developed cerebral venous sinus thrombosis, or CVST, in combination with low blood platelets within about two weeks of receiving the shot.

The Food and Drug Administration and CDC on April 13 asked states to temporarily halt using J&J's vaccine "out of an abundance of caution" following reports of the rare blood clots. Within hours of the warning, more than a dozen states as well as some national pharmacies halted inoculations with J&J's vaccine, some replacing scheduled appointments with either the Pfizer or Moderna vaccine. Rare blood clots with low platelets are occurring at a rate of 7 per 1 million vaccinations in women ages 18 to 49 for the J&J shot and 0.9 per 1 million in women age 50 and older, according to a slide presented at the CDC panel meeting. CDC has confirmed 15 cases total of rare blood clot conditions, which includes 12 women who developed blood clots in the brain. Three women have died and 7 remained hospitalized, according to the slides. There are no confirmed cases in men, though officials have said they are reviewing potential additional cases.

A CDC model presented at the meeting showed not resuming the use of J&J's vaccine would delay immunizing all adults intending to get the shots by 14 days. J&J executives told the committee the benefits of its vaccine still outweighed its risks, adding that the shots would prevent deaths and hospitalizations. They suggested a new warning label for the vaccine that explains the risk of blood clots.

Space

What Do You Call a Bunch of Black Holes? (nytimes.com) 155

What do you call a collection of black holes? The question has taken on an urgency among astronomers inspired by the recent news of dozens of black holes buzzing around the center of a nearby cluster of stars. The New York Times: In the last few years, instruments like the LIGO and Virgo gravitational-wave detectors have recorded space-time vibrations from the collisions of black holes, making it clear beyond doubt that these monstrous concentrations of nothingness not only exist but are ubiquitous. Astronomers anticipate spotting a great number of these Einsteinian creatures when the next generation of gravitational-wave antennas are deployed. What will they call them? There are gaggles of geese, pods of whales and murders of crows. What term would do justice to the special nature of black holes? A mass? A colander? A scream?

Jocelyn Kelly Holley-Bockelmann, an astrophysicist at Vanderbilt University, and colleagues are developing an international project called the Laser Interferometer Space Antenna, or LISA, that will be able to detect collisions between all sizes of black holes throughout the universe. She was trying to run a Zoom meeting of the group recently "when one of the members said his daughter was wondering what you call a collective of black holes -- and then the meeting fell apart, with everyone trying to up one another," she said in an email. "Each time I saw a suggestion, I had to stop and giggle like a loon, which egged us all on more." The question was crowdsourced on Twitter recently as part of what NASA has begun calling black hole week (April 12-16). Among the many candidates so far: A crush. A mosh pit. A silence. A speckle. A hive. An enigma. Or a favorite of mine for of its connection to my youth: an Albert Hall of black holes.

Slashdot Top Deals