Science

Man Can Change His Pupil Size On Command (livescience.com) 84

An anonymous reader quotes a report from Live Science: A 23-year-old student in Germany can shrink and enlarge his pupils on demand, according to a new case report -- a feat that was previously thought to be impossible. Two tiny opposing muscles in the eye act as puppeteers of each pupil (the dark center of the eye), dilating or enlarging them in a dark environment to let in more light and constricting them in a bright environment to limit the amount of light that flows in. This process was thought to be completely automatic; when you step into a dark room, you don't have to consciously tell your pupils to change size. Pupils can also change size in response to other factors, such as increases in arousal. It was previously known that some people can change their pupil size at will, but by using indirect methods.

[N]o one thought it was possible to change pupil size by directly controlling it like a muscle -- that is, until a student of psychology at Ulm University in Germany contacted Strauch after taking one of his courses. (Strauch was previously a doctoral student at Ulm University). When he was about 15 or 16 years old, the young man -- identified in the case report by his initials, D.W. -- realized that he could change the size of his pupils. "I showed a friend that I can 'tremble' with my eyeballs, and he noticed that my pupils became small," D.W. told Strauch and his colleagues at Ulm University. But D.W. didn't notice that he had this ability until he played computer games for long periods of time. "Constricting the pupil feels like gripping, tensing something; making it larger feels like fully releasing, relaxing the eye," D.W. told the researchers.

Through a series of tests, the researchers confirmed that D.W. indeed had this ability -- and they found no indication that he was changing the size of his pupils indirectly. In one test, the researchers measured the electrical properties of the skin by applying voltage to test whether he was aroused by increased mental effort, which also might have increased his pupil size indirectly. Without using any indirect method, D.W. could dilate his pupils up to 0.09 inches (2.4 millimeters) in diameter and constrict them to 0.03 inches (0.88 mm) in diameter. What's more, even at the closest point an object can be for the eye to still see it in focus, in which the pupil is already "maximally" constricted, D.W. could voluntarily constrict his pupil even more. By doing this, D.W. improved his focus and could see objects clearly nearly two times closer to his face than he could if he wasn't controlling his pupil size. Using a type of brain scan known as functional magnetic resonance imaging (fMRI), the researchers found increased activation of certain parts of the brain involved in volition, or the ability to decide and do something out of free will. The researchers can't say for sure that D.W. was directly controlling his pupils, but from their many tests, they did not find any evidence that he was using indirect strategies.
The findings were published in the International Journal of Psychophysiology.
Medicine

Where Did Ivermectin Come From and Why Are Americans Taking It To Try and Treat COVID-19? (wfaa.com) 676

Ivermectin is making the rounds again online after Joe Rogan casually mentioned he took the drug after testing positive for COVID-19. Some researchers claim it helps treat symptoms of the virus; others, including the U.S. Food and Drug Administration (FDA), have yet to make that determination. "While there are approved uses for ivermectin in people and animals, it is not approved for the prevention or treatment of COVID-19," the FDA says in a FAQ.

So where did this drug come from and why have people been using it to try and treat COVID-19? WFAA, an ABC-affiliated television station licensed to Dallas, Texas, helps answer those questions: In the 1970s, Japanese biochemist Satoshi Omura discovered the avermectin family of compounds, which are a series of drugs used to treat parasites and insect pests. Ivermectin is one of these drugs. Ivermectin has a mixture of carbon, hydrogen and oxygen. It was modified and first introduced as medicine in 1981. It soon became registered around the world to treat parasitic worms in cattle, sheep, and other animals. It can be taken as a pill or applied to the skin depending on why it's needed.

By 1988, ivermectin was approved as a medical treatment in humans. This "wonder drug," as many called it, was prescribed to treat illnesses, which include head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis, and lymphatic filariasis. Since its discovery, ivermectin has been used by more than 700 million people in the world specifically to treat river blindness and lymphatic filariasis, according to a National Institutes of Health study.

A medical study led by Dr. Ahmed Elgazzar in Egypt was published in November 2020. It said that hospitalized patients with COVID-19 who received this antiparasitic drug improved more quickly and had a better chance of staying alive. It was retracted in July. Multiple medical agencies -- including the Centers for Disease Control (CDC), Food and Drug Administration (FDA) and National Institutes of Health (NIH) -- have been unable to find any evidence this drug helps with COVID-19. The CDC put out a press release in August, making clear that ivermectin is not authorized or approved by the FDA for the prevention or treatment of COVID-19. In that same CDC press release, health experts also warned about the dangers that can come from taking ivermectin incorrectly.

Science

The New Thermodynamic Understanding of Clocks (quantamagazine.org) 53

Studies of the simplest possible clocks have revealed their fundamental limitations -- as well as insights into the nature of time itself. Natalie Wolchover, writing for Quanta Magazine: [...] Over the past five years, through studies of the simplest conceivable clocks, the researchers have discovered the fundamental limits of timekeeping. They've mapped out new relationships between accuracy, information, complexity, energy and entropy -- the quantity whose incessant rise in the universe is closely associated with the arrow of time. These relationships were purely theoretical until this spring, when the experimental physicist Natalia Ares and her team at the University of Oxford reported measurements of a nanoscale clock that strongly support the new thermodynamic theory.

Nicole Yunger Halpern, a quantum thermodynamicist at Harvard University who was not involved in the recent clock work, called it "foundational." She thinks the findings could lead to the design of optimally efficient, autonomous quantum clocks for controlling operations in future quantum computers and nanorobots. The new perspective on clocks has already provided fresh fodder for discussions of time itself. "This line of work does grapple, in a fundamental way, with the role of time in quantum theory," Yunger Halpern said. Gerard Milburn, a quantum theorist at the University of Queensland in Australia who wrote a review paper last year about the research on clock thermodynamics, said, "I don't think people appreciate just how fundamental it is."

Social Networks

Reddit's Teach-the-Controversy Stance On COVID Vaccines Sparks Wider Protest (arstechnica.com) 582

An anonymous reader quotes a report from Ars Technica, written by Jon Brodkin: Over 135 subreddits have gone dark this week in protest of Reddit's refusal to ban communities that spread misinformation about the COVID pandemic and vaccines. Subreddits that went private include two with 10 million or more subscribers, namely r/Futurology and r/TIFU. The PokemonGo community is one of 15 other subreddits with at least 1 million subscribers that went private; another 15 subreddits with at least 500,000 subscribers also went private. They're all listed in a post on "r/VaxxHappened" which has been coordinating opposition to Reddit management's stance on pandemic misinformation. More subreddits are being added as they join the protest.

Last week, the moderators of over 450 subreddits joined an open letter urging Reddit to "take action against the rampant Coronavirus misinformation on their website," saying that subreddits existing "solely to spread medical disinformation and undermine efforts to combat the global pandemic should be banned." Reddit published a response defending its stance, saying it will continue to allow "debate" and "dissent" on vaccines and other COVID-related matters even when it "challenge[s] consensus views."

"We appreciate that not everyone agrees with the current approach to getting us all through the pandemic, and some are still wary of vaccinations. Dissent is a part of Reddit and the foundation of democracy," the company said. Reddit does draw a line somewhere, as it said it will continue to take action against communities "dedicated to fraud (e.g. fake vaccine cards) or encouraging harm (e.g. consuming bleach)." But in general, Reddit said, "we believe it is best to enable communities to engage in debate and dissent, and for us to link to the CDC wherever appropriate."

Medicine

Rugby: Head Impact Study Shows Cognitive Decline After Just One Season (bbc.com) 47

Researchers from the University of South Wales found that over just one season a team of professional rugby players saw a decline in blood flow to the brain and cognitive function -- the ability to reason, remember, formulate ideas and perform mental gymnastics. The paper also suggests that rather than only concussions, repetitive contacts, or sub concussions, sustained through rugby have caused the declines seen in the players. The BBC reports: Some studies suggest professional rugby players may be exposed to 11,000 contact events per season, and more research is beginning to show evidence that it may not be concussions alone that could impact the brain, but the cumulative effect and volume of contact events too. The peer reviewed University of South Wales study, which is funded by the Royal Society Wolfson Research Fellowship, recorded six concussion incidents among all the players that took part over the course of the year. However, all of those involved in the study saw a decline in blood flow to the brain and cognitive function between pre and post-season results.

Further findings include a correlation between an increase in contact amount, playing position and rate of decline on the main measures tested. The university team are also working on a similar study, comparing current players and retired players against a control group to determine whether there is a faster rate of decline in brain function in rugby players. They say more research is needed on the long term effects of such a decline.
In a statement responding to the University of South Wales research, the sport's governing body World Rugby said: "World Rugby welcomes all research that can inform and support our recently launched strategy to cement rugby as the most progressive sport on player welfare. It is at the heart of everything that we say and do as a sport. World Rugby recently committed to double our investment in player welfare and new concussion research and initiatives. We are currently undertaking a wide-ranging evaluation of contact training volume across the game and look forward to the results of the ongoing Otago Rugby Community Head Impact Detection study using instrumented mouthguards, which is the largest study of playing and training head impacts in men's and women's community rugby."
Biotech

Theranos Founder Elizabeth Holmes On Trial As Jury Selection Begins (arstechnica.com) 86

An anonymous reader quotes a report from Ars Technica, written by Tim De Chant: Nearly a decade ago, Theranos touted a revolutionary diagnostic device that could run myriad medical tests without having to draw blood through a needle. Today, the startup's founder, Elizabeth Holmes, goes to court, where she's facing 12 criminal counts for statements she made to investors and consumers about her company's technology. Holmes founded Theranos in 2003 after dropping out of Stanford University at the age of 19. Driven by her phobia of needles, Holmes wanted to create diagnostic tests that use blood from finger pricks rather than from needles. The idea caught on, attracting well-connected board members like Henry Kissinger and James Mattis, drawing over $400 million in investments from wealthy investors including Larry Ellison and Rupert Murdoch, and securing lucrative partnerships with Walgreens and Safeway. At its peak, Theranos was worth over $9 billion. But Theranos' myth started unwinding in 2015 when a Wall Street Journal investigation revealed that the company had been performing most of its tests on traditional blood diagnostic machines rather than its own "Einstein" device. The company's own employees doubted the machine's accuracy.

Holmes and [Ramesh "Sunny" Balwani, Theranos' president and chief operating officer] were indicted in June 2018, and soon Theranos was facing mounting civil and criminal investigations. The company settled a Securities and Exchange Commission probe and shut down shortly thereafter. The end of Theranos didn't halt the scrutiny of Holmes' and Balwani's behavior, though. Three rounds of indictments have brought the total to 10 counts of wire fraud and two counts of conspiracy to commit wire fraud. The latest indictment, which supersedes the previous two, was filed in June 2020. Both Holmes and Balwani have pleaded not guilty, and Balwani's trial will begin next year. The indictments aren't limited to claims about the company's proprietary diagnostic machine but also include what Holmes and Balwani allegedly said to investors about revenue and business deals. The prosecution says the pair told investors that Theranos would bring in over $100 million in revenue in 2014, helping the company break even, and hit $1 billion in 2015, amounts that exceeded the executives' actual expectations. Prosecutors also say that the pair falsely told investors that the company landed contracts with the Pentagon.

The road to trial has been filled with delays, first due to the COVID-19 pandemic and then again when Holmes became pregnant. Her child was born in July, around the time the trial was supposed to begin. If convicted, Holmes faces up to 20 years in prison. Today's proceedings kick off jury selection, in which prosecutors and defense attorneys will begin questioning over 100 potential jurors. [...] Opening statements are scheduled to begin on September 8, and the trial may run through mid-December. Holmes is expected to claim that Balwani, who was her boyfriend for much of Theranos' existence, was an abusive and controlling partner. A court filing released on Saturday revealed that Holmes is expected to take the stand during the trial and allege that he monitored her calls, texts, and emails and was physically violent, claims that Balwani denies. Her attorneys say these actions affected her "state of mind" when the alleged fraud took place.

Earth

Satellites Spot Oceans Aglow With Trillions of Organisms (nytimes.com) 23

A new generation of detectors let scientists identify a dozen large episodes of bioluminescence, one a hundred times larger than Manhattan -- and that's the smallest. From a report: The ocean has always glowed. The Greeks and Romans knew of luminous sea creatures as well as the more general phenomenon of seawater that can light up in bluish-green colors. Charles Darwin, as he sailed near South America on a dark night aboard the H.M.S. Beagle, encountered luminescent waves. He called it "a wonderful and most beautiful spectacle." As far as the eye could see, he added, "the crest of every wave was bright" -- so much so that the "livid flames" lit the sky. Now, scientists report that ocean bioluminescence can be so intense and massive in scale that satellites orbiting five hundred miles high can see glowing mats of microorganisms as they materialize in the seas. Last month in the journal Scientific Reports, eight investigators told of finding a luminous patch south of Java in 2019 that grew to be larger than the combined areas of Vermont, New Hampshire, Massachusetts, Rhode Island and Connecticut.

"It was an epiphany," said Steven D. Miller, lead author on the bioluminescence study and a specialist in satellite observations at Colorado State University. When a hidden wonder of nature comes to light, he added, "it captures your imagination." The scientists said the close examination of images gathered between December 2012 and March 2021 from a pair of satellites let them identify a dozen extremely large events -- approximately one every eight months. Even the smallest was a hundred times larger than Manhattan. The imagery is opening a new window on the world's oceans, scientists say, and promises to aid the tracking and study of the glowing seas, whose origins are poorly understood. Kenneth H. Nealson, a pioneer of bioluminescence research at the University of Southern California, called the discovery "a big step toward being able to understand" how an enduring mystery of the sea "actually comes to be."

Science

Toxic 'Forever Chemicals' Contaminate Indoor Air at Worrying Levels, Study Finds (theguardian.com) 70

Toxic PFAS compounds are contaminating the air inside homes, classrooms and stores at alarming levels, a new study has found. From a report: Researchers with the University of Rhode Island and Green Science Policy Institute tested indoor air at 20 sites and detected the "forever chemicals" in 17 locations. The airborne compounds are thought to break off of PFAS-treated products such as carpeting and clothing and attach to dust or freely float through the indoor environment. Experts previously considered food and water to be the two main routes by which humans are exposed to PFAS, but the study's authors note that many humans spend about 90% of their time indoors, and the findings suggest that breathing in the chemicals probably represents a third significant exposure route. "It's an underestimated and potentially important source of exposure to PFAS," said Tom Bruton, a co-author and senior scientist at Green Science.

PFAS, or per- and polyfluoroalkyl substances, are a class of about 9,000 compounds used to make products water-, stain- or heat-resistant. Because they are so effective, the chemicals are used across dozens of industries and are in thousands of everyday consumer products such as stain guards, carpeting and shoes. Textile manufacturers use them to produce waterproof clothing, and they are used in floor waxes, nonstick cookware, food packaging, cosmetics, firefighting foam and much more. PFAS are dubbed "forever chemicals" because they do not naturally break down. They accumulate in animals, including humans, and are linked to cancer, birth defects, liver disease, thyroid disease, decreased immunity, hormone disruption and a range of other serious health problems. A February Guardian analysis of household products found fluorine, an indicator of PFAS, present in 15 items. The chemicals are so widely used that it is difficult to say with precision where all the airborne PFAS are coming from, though the new study also detected their presence in carpets and clothing at some sites.

Space

One-Third of Sun-Like Stars May Have Eaten Their Planets (sciencemag.org) 38

sciencehabit shares a report from Science Magazine, written by Adam Mann: Like the Greek god Chronos, a good number of stars devour their children. As many as one-third of them have swallowed one or more of their own planets, a new study suggests. The findings could help astronomers rule out stellar systems unlikely to contain Earth-like worlds. The team investigated how often this happens by looking at 107 binary systems containing two Sun-like stars -- akin to the fictional two-sunned world Tatooine in Star Wars. In 33 of these pairs, one of the companions showed elevated levels of iron compared with the other, a sign of planetary cannibalism. These same partners were also rich in lithium, giving further credence to the world-munching hypothesis. Although Sun-like stars are born with substantial amounts of lithium, they burn it away within the first 100 million years of their lives, so seeing it in the older stars in the study sample indicated it likely came from a planet. Using these different lines of evidence, the team was able to model that between 20% and 35% of Sun-like stars consume a few Earths' worth of their offspring. Such events could happen in systems where gravitational interactions among the planets would either fling one into the central star or bring it close enough for the star to slowly vaporize and devour it. The findings have been published in the journal Nature Astronomy.
ISS

Russian Cosmonauts Find New Cracks In ISS Module (livescience.com) 102

Mr.Fork shares a report from Live Science: Russian cosmonauts discovered cracks on the Zarya module of the International Space Station (ISS) and are concerned that the fissures could spread over time, a senior space official reported on Monday. "Superficial fissures have been found in some places on the Zarya module," Vladimir Solovyov, chief engineer of rocket and space corporation Energia, told RIA news agency, according to Reuters. "This is bad and suggests that the fissures will begin to spread over time." The Zarya module, also called the Functional Cargo Block, was the first component of the ISS ever launched, having blasted into orbit on Nov. 20, 1998, according to NASA. Solovyov recently stated that the ISS is beginning to show its age and warned that there could potentially be an "avalanche" of broken equipment after 2025, according to Reuters.
United States

Five Decades Later, Medicare Might Cover Dental Care (nytimes.com) 158

Tens of millions of older Americans who cannot afford dental care -- with severe consequences for their overall health, what they eat and even when they smile -- may soon get help as Democrats maneuver to add dental benefits to Medicare for the first time in its history. From a report: The proposal, part of the large budget bill moving through Congress, would be among the largest changes to Medicare since its creation in 1965 but would require overcoming resistance from dentists themselves, who are worried that it would pay them too little.
Power

So How Close Are We Now to Nuclear Fusion Energy? (theguardian.com) 180

For a fraction of a second, 10 quadrillion watts of fusion power were produced this month by researchers at Lawrence Livermore National Laboratory.

The author of The Star Builders: Nuclear Fusion and the Race to Power the Planet explains what might happen next: The aim of these experiments is — for now — to show proof of principle only: that energy can be generated. The team behind the success are very close to achieving this: they have managed a more than 1,000-fold improvement in energy release between 2011 and today. Prof Jeremy Chittenden, co-director of the Centre for Inertial Fusion Studies at Imperial College London, said last month that "The pace of improvement in energy output has been rapid, suggesting we may soon reach more energy milestones, such as exceeding the energy input from the lasers used to kickstart the process...."

Many recent advances have been made with a different type of fusion device, the tokamak: a doughnut-shaped machine that uses a tube of magnetic fields to confine its fuel for as long as possible. China's Experimental Advanced Superconducting Tokamak (East) set another world record in May by keeping fuel stable for 100 seconds at a temperature of 120m degrees celsius — eight times hotter than the sun's core. The world's largest ever magnetic fusion machine, Iter, is under construction in the south of France and many experts think it will have the scale needed to reach net energy gain. The UK-based Joint European Torus (Jet), which holds the current magnetic fusion record for power of 67%, is about to attempt to produce the largest total amount of energy of any fusion machine in history. Alternative designs are also being explored: the UK government has announced plans for an advanced tokamak with an innovative spherical geometry, and "stellarators", a type of fusion device that had been consigned to the history books, are enjoying a revival having been enabled by new technologies such as superconducting magnets.

This is a lot of progress, but it's not even the biggest change: that would be the emergence of private sector fusion firms. The recently formed Fusion Industry Association estimates that more than $2bn of investment has flooded into fusion startups. The construction of experimental reactors by these firms is proceeding at a phenomenal rate: Commonwealth Fusion Systems, which has its origins in MIT research, has begun building a demonstration reactor in Massachusetts; TAE Technologies has just raised $280m to build its next device; and Canadian-based General Fusion has opted to house its new $400m plant in the UK. This will be constructed in Oxfordshire, an emerging hotspot for the industry that is home to private ventures First Light Fusion and Tokamak Energy as well as the publicly funded Jet and Mast (Mega Amp Spherical Tokamak) Upgrade devices run by the UK Atomic Energy Authority...

For now, publicly funded labs are producing results a long way ahead of the private firms — but this could change.

"Whether commercial fusion energy is ready in time to help with global warming or not depends on us as a society and how badly we want — no, need — star power on our side," the author concludes.

He also calls fusion energy "the only feasible way we can explore space beyond Earth's immediate vicinity."
Science

Police Raid on Fossil Traders Found an Amazing Prehistoric Flying Reptile Skeleton (cnet.com) 27

CNET reports: A fossil discovered during a police raid in Brazil has turned out to be one of the best-preserved flying reptiles found yet, researchers say.

The remains belong to a tapejarid, a toothless pterosaur from the early Cretaceous period known for its huge cranial crest composed partly of bone and partly of soft tissue. Skulls and partial skeletons of Brazilian tapejarids have turned up before, but this fossil was found with more than 90% of its skeleton intact, along with some soft tissue in place around the bones.

"This fossil is special because it is the most complete pterosaur from Brazil and it brings new information about the anatomy and ecology of this animal," says Victor Beccari, co-author of a study on the find published Wednesday in the open-access journal PLOS One.

Brazilian federal police found the tapejarid fossil while investigating an illegal fossil trade operation in 2013. They recovered 3,000 specimens kept in storage units in the states of São Paulo, Minas Gerais and Rio de Janeiro and transferred them to the Geosciences Institute of the University of São Paulo for study. Since 1942, Brazilian law has categorized fossils as state property, as they're considered part of the country's geological heritage and forbidden from being sold commercially.

The tapejarid had a wingspan of more than 8 feet (2.5 meters) and stood 3.2 feet (1 meter) tall. Its head crest accounted for 40% of its height.
The Courts

Elizabeth Holmes Might Accuse Ex-Boyfriend/Former Theranos Executive of Psychological Abuse (cnn.com) 116

Slashdot reader Charlotte Web quotes CNN: Elizabeth Holmes, the disgraced founder and former CEO of Theranos whose criminal trial is set to begin in a matter of days, is likely to defend herself by claiming she was the victim of a decade-long abusive relationship with her ex-boyfriend, also a former Theranos executive, court documents reveal.

According to the newly unsealed documents, Holmes plans to have an expert testify about the psychological, emotional and sexual abuse she experienced from Ramesh "Sunny" Balwani, who served as the company's COO, including the abusive tactics he allegedly used to "exert control" as well as the psychological impact. Balwani, according to a court filing, "adamantly denies" the claims. Holmes is also "likely to testify herself to the reasons why she believed, relied on, and deferred to Mr. Balwani," according to a filing from Holmes' attorney. In a separate filing from Balwani's attorneys, they acknowledge Holmes' plans to introduce evidence that Balwani verbally disparaged her, controlled what she ate, how she dressed, and who she interacted with, "essentially dominating her and erasing her capacity to make decisions." The filing calls the allegations "deeply offensive to Mr. Balwani" and "devastating personally to him...."

Balwani, a former software executive, joined Theranos in 2009, becoming Holmes' second-in-command. Nearly 20 years Holmes' senior, the pair had met in 2002 on a trip to Beijing through Stanford University's Mandarin program.

Balwani's case is slated to begin in 2022 after the completion of Holmes' trial.

Medicine

Reducing Sugar In Packaged Foods Can Prevent Disease In Millions, Study Finds (massgeneral.org) 229

Long-time Slashdot reader schwit1 quotes a new press release from Massachusetts General Hospital: Cutting 20% of sugar from packaged foods and 40% from beverages could prevent 2.48 million cardiovascular disease events (such as strokes, heart attacks, cardiac arrests), 490,000 cardiovascular deaths, and 750,000 diabetes cases in the U.S. over the lifetime of the adult population, reports a study published in Circulation...

More than two in five American adults are obese, one in two have diabetes or prediabetes, and nearly one in two have cardiovascular disease, with those from lower-income groups being disproportionately burdened.

Their model suggests that after 10 years, America could save $4.28 billion in total net healthcare costs, and $118.04 billion over the lifetime of the current adult population (ages 35 to 79), according to the announcement.

It also points out that America "lags other countries in implementing strong sugar-reduction policies." And the study's co-senior author (also a dean of the Friedman School of Nutrition Science and Policy at Tufts University) says their findings "suggest it's time to implement a national program with voluntary sugar reduction targets, which can generate major improvements in health, health disparities, and healthcare spending in less than a decade."
Space

After 'Sideways' Launch, Space Startup Astra's Rocket Fails to Reach Orbit (space.com) 60

California Bay Area space startup Astra "attempted its third orbital test flight today, sending its two-stage Launch Vehicle 0006 skyward from the Pacific Spaceport Complex on Alaska's Kodiak Island at 6:35 p.m. EDT (2235 GMT)," reports Space.com.

"The rocket suffered an anomaly about 2.5 minutes after liftoff, however, and the flight was terminated." Something appeared to be wrong from the beginning, as Launch Vehicle 0006 lurched sideways at the moment of liftoff rather than rise smoothly off the pad. But the rocket recovered and soared high into the Alaska sky, reaching an altitude of about 20.5 miles (33 kilometers) before shutting down, according to real-time data Astra provided during a webcast of the launch. The mission was terminated right around "max q," the point when the mechanical stresses on a rocket are highest. A camera mounted on Launch Vehicle 0006 appeared to show a piece of the booster breaking loose around that time.

"Although we did not achieve our primary objective today, our team will work hard to determine what happened here," Carolina Grossman, director of product management at Astra, said during today's launch webcast. "And as we dig into the flight data, we are optimistic about the future and our next attempt...." Initial analyses show that one of the rocket's five first-stage engines failed about 1 second after liftoff, for reasons that weren't immediately clear, Astra co-founder, chairman and CEO Chris Kemp said in a short postflight briefing this evening... "It was obviously not successful at putting anything in orbit, but it was a flight where we learned a tremendous amount of obviously things we need to look into as we prepare to return to Kodiak and fly again," he added...

[T]oday's launch was the first of two booked by the U.S. Space Force; the second was expected to lift off later this year, though that timeline could end up shifting a bit. Astra holds a number of other contracts as well: The company has signed deals for more than 50 launches that together represent more than $150 million in revenue, Kemp told Space.com last month... And over the long haul, the company plans to ramp up its launch cadence to an unprecedented level, potentially transforming humanity's access to space.

"Our next objective is monthly, then weekly, and finally daily space delivery," Astra co-founder and chief technology officer Adam London said...

Medicine

Calls Grow to Discipline Doctors Spreading Virus Misinformation Online (nytimes.com) 450

The New York Times tells the story of an Indiana physician spreading misinformation about the pandemic. Public health officials say statements like his have contributed to America's vaccine hesitancy and resistance to mask-wearing, exacerbating the pandemic. His videos "have amassed nearly 100 million likes and shares on Facebook, 6.2 million views on Twitter, at least 2.8 million views on YouTube and over 940,000 video views on Instagram." His talk's popularity points to one of the more striking paradoxes of the pandemic. Even as many doctors fight to save the lives of people sick with Covid-19, a tiny number of their medical peers have had an outsize influence at propelling false and misleading information about the virus and vaccines.

Now there is a growing call among medical groups to discipline physicians spreading incorrect information. The Federation of State Medical Boards, which represents the groups that license and discipline doctors, recommended last month that states consider action against doctors who share false medical claims, including suspending or revoking medical licenses. The American Medical Association says spreading misinformation violates the code of ethics that licensed doctors agree to follow.

"When a doctor speaks, people pay attention," said Dr. Humayun Chaudhry, president of the Federation of State Medical Boards. "The title of being a physician lends credibility to what people say to the general public. That's why it is so important that these doctors don't spread misinformation."

Japan

Japan Successfully Tests Possible Deep-Space Rocket Technology (futurism.com) 40

Futurism reports: Japan's space agency JAXA has announced that is has successfully demonstrated the operation of a "rotary detonation engine" in space, a world's first.

Such an engine uses a series of controlled explosions that travel around a circular channel at its base. The result is a massive amount of thrust coming from a much smaller engine using significantly less fuel — a potential game changer for deep space exploration, according to JAXA. It's a lucrative endeavor and Japan isn't the only country pursuing the idea. Researchers across the U.S. are testing out the technology to make rockets both lighter and more environmentally friendly...

"We will aim to put the technology into practical use in about five years,"Jiro Kasahara, a Nagoya University professor who is working on the technology with JAXA, told the Japan Times last month.

Ars Technica reports that detonation engines should theoretically weigh less than traditional rocket engines &mdash and that JAXA "plans to use data from this test for potential development of detonation engines for kick stages as well as first- and second-stage rocket engines."

Futurism adds that in the same flight JAXA also successfully tested a second "pulse detonation engine."
Medicine

Previous Covid Prevents Delta Infection Better Than Pfizer Shot (bloomberg.com) 311

An anonymous reader quotes a report from Bloomberg: People who recovered from a bout of Covid-19 during one of the earlier waves of the pandemic appear to have a lower risk of contracting the delta variant than those who got two doses of the vaccine from Pfizer and BioNTech SE. The largest real-world analysis (PDF) comparing natural immunity -- gained from an earlier infection -- to the protection provided by one of the most potent vaccines currently in use showed that reinfections were much less common. The paper from researchers in Israel contrasts with earlier studies, which showed that immunizations offered better protection than an earlier infection, though those studies were not of the delta variant.

The results are good news for patients who already successfully battled Covid-19, but show the challenge of relying exclusively on immunizations to move past the pandemic. People given both doses of the Pfizer-BioNTech vaccine were almost six-fold more likely to contract a delta infection and seven-fold more likely to have symptomatic disease than those who recovered. The analysis also showed that protection from an earlier infection wanes with time. The risk of a vaccine-breakthrough delta case was 13-fold higher than the risk of developing a second infection when the original illness occurred during January or February 2021. That's significantly more than the risk for people who were ill earlier in the outbreak. Giving a single shot of the vaccine to those who had been previously infected also appeared to boost their protection. The long-term benefit of a booster dose of the inoculation, which has just recently begun in Israel, is unknown.

Space

China Researching Challenges of Kilometer-Scale Ultra-large Spacecraft (spacenews.com) 98

Hmmmmmm shares a report from SpaceNews: The National Natural Science Foundation of China has outlined a five-year project for researchers to study the assembly of ultra-large spacecraft. Scientists are being directed to meet the "urgent need" for the construction of ultra-large spacecraft. Preliminary research is to include studying the challenges of developing lightweight structures and subsequent on-orbit assembly and control. Though vague, the project would have practical applications for potential megaprojects including colossal space-based solar power stations. Such facilities would be based in geostationary orbit and span kilometers. These stations would collect solar energy and transmitting power to Earth through microwaves.

Kilometer-scale, ultra-large spacecraft are described as "major strategic aerospace equipment for the future use of space resources, exploration of the mysteries of the universe, and long-term habitation in orbit," according to the project outline within the mathematical and physical sciences attachment to the released document. The plan, if approved, would aim for commercial, on-orbit gigawatt-level power generation by 2050. This would require more than 100 super heavy-lift Long March 9 launches and around 10,000 tons of infrastructure, assembled in orbit, according to Long Lehao, a chief designer of China's Long March rocket series.

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