Space

Could 'Ghost Particle' Neutrinos Crashing Into Antarctica Change Astronomy Forever? (cnet.com) 29

CNET reports on how research in Antarctica "could change astronomy forever": About 47 million light-years from where you're sitting, the center of a black-hole-laden galaxy named NGC 1068 is spitting out streams of enigmatic particles. These "neutrinos" are also known as the elusive "ghost particles" that haunt our universe but leave little trace of their existence.... Nestled into about 1 billion tons of ice, more than 2 kilometers (1.24 miles) beneath Antarctica, lies the IceCube Neutrino Observatory. A neutrino hunter, you might call it. When any neutrinos transfer their party to the frigid continent, IceCube stands ready.

In a paper published Friday in the journal Science, the international team behind this ambitious experiment confirmed it has found evidence of 79 "high-energy neutrino emissions" coming from around where NGC 1068 is located, opening the door for novel — and endlessly fascinating — types of physics. "Neutrino astronomy," scientists call it.

It'd be a branch of astronomy that can do what existing branches simply cannot.

Before today, physicists had only shown neutrinos coming from either the sun; our planet's atmosphere; a chemical mechanism called radioactive decay; supernovas; and — thanks to IceCube's first breakthrough in 2017 — a blazar, or voracious supermassive black hole pointed directly toward Earth. A void dubbed TXS 0506+056. With this newfound neutrino source, we're entering a new era of the particle's story. In fact, according to the research team, it's likely neutrinos stemming from NGC 1068 have up to millions, billions, maybe even trillions the amount of energy held by neutrinos rooted in the sun or supernovas. Those are jaw-dropping figures because, in general, such ghostly bits are so powerful, yet evasive, that every second, trillions upon trillions of neutrinos move right through your body. You just can't tell....

Not only is this moment massive because it gives us more proof of a strange particle that wasn't even announced to exist until 1956, but also because neutrinos are like keys to our universe's backstage. They hold the capacity to reveal phenomena and solve puzzles we're unable to address by any other means, which is the primary reason scientists are trying to develop neutrino astronomy in the first place.... Expected to be generated behind such opaque screens filtering our universe, these particles can carry cosmic information from behind those screens, zoom across great distances while interacting with essentially no other matter, and deliver pristine, untouched information to humanity about elusive corners of outer space.

The team says their data can provide information on two great unsolved mysteries in astronomy: why black holes emit sporadic blasts of light, and neutrinos' suspected role in the origin of cosmic rays.
Medicine

Psychedelic Mushroom Dose Can Treat Stubborn Depression, Trial Suggests (msn.com) 54

The Washington Post reports: Psilocybin, the active hallucinogen found in psychedelic mushrooms — also known as "magic mushrooms" — can effectively alleviate a severe bout of depression when administered in a single dose and combined with talk therapy, a new clinical study found.

Adults with depression who were administered a single 25-miligram dose of psilocybin were more likely to experience significant improvements in their mental health — both immediately and for up to three months — than others who were randomly assigned smaller doses of the same drug, said the peer-reviewed study, which was published Wednesday in the New England Journal of Medicine....

The trial's findings could be an encouraging sign for the 16 million Americans estimated each year by the Centers for Disease Control and Prevention to have depression, many of whom struggle to find treatments that work for them. Its authors hope the study — which was relatively small, with just 79 participants receiving the 25 mg dose — will pave the way for eventual regulatory approval of psilocybin by the Food and Drug Administration for use as a drug against depression....

Notwithstanding the headaches, nausea and dizziness reported by many as adverse side effects, most of the adults enjoyed the experience.

The Post got an interesting reponse from James Rucker, a consultant psychiatrist at King's College London who worked on the trial. He said there's something about the psychedelic experience that leads to a rapid resolution of depression symptoms, adding "We don't really know what that is at the moment, but it's very different to standard antidepressants...."

"What people forget about psychedelics is that they were being used as medicines prior to 1971 when they essentially got caught up in the drugs war," Rucker added. "We're just picking up the baton of history."

Thanks to Slashdot reader Shmoodling for submitting the story.
Medicine

Pfizer Study Says the Updated COVID Boosters Significantly Rev Up Protection (go.com) 268

The Associated Press reports that Pfizer's updated COVID-19 booster "significantly revved up adults' virus-fighting antibodies, the company said Friday, releasing early findings from a rigorous study of the new shots." Booster doses tweaked to target the most common omicron strain rolled out in early September, and the Food and Drug Administration said the latest data should spur more Americans to get one — especially before another expected wave of cases as people travel for Thanksgiving. Pfizer said people 55 and older who got the omicron-targeting booster had four-fold higher antibody levels than those given an extra dose of the original vaccine....

A month after receiving the new booster, antibody levels in people 55 and older had jumped 13 times higher than before the extra dose. Younger adults saw a 9.5-fold jump, Pfizer and its partner BioNTech said. It had been about 11 months since the study participants' last vaccination....

The new data "reassures us that this was a good decision to move to this bivalent vaccine," FDA vaccine chief Dr. Peter Marks told The Associated Press. "Right now is the time for people to consider going out and get the updated" booster.... The updated doses are combination shots, tailored to offer a boost of protection against both the original coronavirus strain and the dominant BA.5 strain.

Space

Boeing's Starliner Launch Pushed Back To April 2023 61

The first crewed launch of Boeing's Starliner has been delayed again, this time being pushed back to April 2023 from an earlier planned launch date of February. The Register reports: The change came with little announcement from NASA, which tweeted out the new date as a scheduling update without any additional details. In an accompanying blog post, NASA said the change was being made to eliminate conflicts between "visiting spacecraft traffic at the space station," but the agency didn't elaborate much beyond that.

Starliner has been a drag on Boeing since the company unveiled the capsule in 2010. According to Boeing's Q3 2022 filing, Starliner has lost the company $883 million since 2019. That was the year Starliner made its first attempt at an uncrewed launch and docking with the International Space Station, which failed due to a pair of software errors that left it unable to dock and saw it returned to Earth early under less-than-ideal circumstances. Attempts at a second launch in 2021 also failed when 13 of the Calamity Capsule's propulsion system valves failed pre-flight checks. Starliner only made it to the ISS for the first time this past May, but even that launch wasn't without issues as two of the craft's 12 thrusters failed once in orbit.
Space

Virgin Galactic Delays Development of Ship Capable of Higher Flight Rate 26

An anonymous reader shares a report: Space tourism company Virgin Galactic released its third-quarter financial results on Thursday. As one might imagine of a spaceflight company that has not flown since June 2021, the financials are pretty disastrous. The company reported revenue of less than $1 million against losses of more than $146 million. After a long period of downtime, Virgin Galactic officials said the company is close to completing "modifications" of its VMS Eve carrier aircraft and VSS Unity spacecraft.

The company expects to complete a glide flight of Unity, which is released from Eve at altitude, in early 2023. After that point, the company will conduct a powered test flight, likely with its own employees on board, before a research flight for the Italian Air Force. And after that, Virgin Galactic CEO Michael Colglazier said, the company remains on track to begin flying commercial passengers -- people who bought their seats, some more than a decade ago -- in the second quarter of 2023. As with most schedules in spaceflight, that timeline seems pretty optimistic.

This is all well and good, but the return of VSS Unity will not bring Virgin Galactic close to profitability. At an optimal cadence, the company believes it can fly Eve and Unity once a month. This would still leave the company hundreds of millions of dollars in the red on an annual basis. For this reason, the company has always been betting its future on iterations of its spaceship capable of higher flight rates. The ultimate goal is a "Delta" class of spaceship with a turnaround time of one week. With a fleet of Delta ships, Colglazier has told investors, the company can meet a profitable flight rate of 400 missions a year. But the Delta ships are unlikely to be ready for test flights before at least 2025, and commercial service would not begin until a year after that.
Science

Study Urges Caution When Comparing Neural Networks To the Brain (mit.edu) 167

Anne Trafton writes via MIT News: Neural networks, a type of computing system loosely modeled on the organization of the human brain, form the basis of many artificial intelligence systems for applications such speech recognition, computer vision, and medical image analysis. In the field of neuroscience, researchers often use neural networks to try to model the same kind of tasks that the brain performs, in hopes that the models could suggest new hypotheses regarding how the brain itself performs those tasks. However, a group of researchers at MIT is urging that more caution should be taken when interpreting these models.

In an analysis of more than 11,000 neural networks that were trained to simulate the function of grid cells -- key components of the brain's navigation system -- the researchers found that neural networks only produced grid-cell-like activity when they were given very specific constraints that are not found in biological systems. "What this suggests is that in order to obtain a result with grid cells, the researchers training the models needed to bake in those results with specific, biologically implausible implementation choices," says Rylan Schaeffer, a former senior research associate at MIT. Without those constraints, the MIT team found that very few neural networks generated grid-cell-like activity, suggesting that these models do not necessarily generate useful predictions of how the brain works.
Mikail Khona, an MIT graduate student in physics, is also an author. "When you use deep learning models, they can be a powerful tool, but one has to be very circumspect in interpreting them and in determining whether they are truly making de novo predictions, or even shedding light on what it is that the brain is optimizing," says Ila Fiete, the senior author of the paper and professor of brain and cognitive sciences at MIT.

"Deep learning models will give us insight about the brain, but only after you inject a lot of biological knowledge into the model," adds Mikail Khona, an MIT graduate student in physics who is also an author. "If you use the correct constraints, then the models can give you a brain-like solution."
Space

Scientists Discover Huge 'Extragalactic Structure' in Hidden Region of Space (vice.com) 30

Scientists have discovered a huge "extragalactic structure" hidden behind the Milky Way in a mysterious area of the sky known as the "zone of avoidance" because it is obscured by our own galaxy's opaque bulge, according to a new preprint study. Motherboard reports: The discovery of the structure, which appears to be a large galaxy cluster, helps to fill in this shadowy part of our cosmic map, which may as well be labeled "here be space dragons" because it is so unclear what exists there. The star stuff that makes up our galaxy, the Milky Way, is distributed inside a thin plane that orbits around a central bulge that contains a supermassive black hole. The galactic plane and bulge are packed with stars, dust, and gas that block our view of whatever is on the other side. Though scientists have been able to use different wavelengths to peer through the zone of avoidance (ZoA), a region that obscures 10 to 20 percent of the sky, most of this region still remains out of view.

Now, a team led by Daniela Galdeano, an astronomer at the National University of San Juan in Argentina, report the discovery of "a new galaxy cluster, VVVGCl-B J181435-381432, behind the Milky Way bulge," which helps to complete "the picture of the large scale structure in this still little explored area of the sky," according to a study posted this week on the preprint server arxiv. [...] Galdeano and her colleagues were able to spot this cluster within the ZoA using the VVV Survey, a project that scans the Milky Way bulge at infrared wavelengths using the European Southern Observatory's Visible and Infrared Survey Telescope for Astronomy (VISTA) in Paranal, Chile. Whereas the galactic plane blocks out almost all visible light in the zone, longer wavelengths of light, including in the infrared band, are able to travel through the Milky Way's haze to reach telescopes on Earth.

To zoom in on the tantalizing region, the researchers used a near-infrared instrument called FLAMINGOS-2, which is on the Gemini South telescope in Chile, to identify measurements called "redshifts" that can be used to estimate the distance and velocities of its objects in space. The results exposed new details about five galaxies some three billion light years away, which the researchers think are part of a much bigger cluster. The team estimated that the cluster contains about 58 galaxies, but it will take more observations to be sure of its mass and contents.

Science

Scientists Zap Clouds With Electricity To Make Them Rain 29

A new experiment has shown that zapping clouds with electrical charge can alter droplet sizes in fog or, potentially, help a constipated cloud to rain. From a report: Last year Giles Harrison, from the University of Reading, and colleagues from the University of Bath, spent many early mornings chasing fogs in the Somerset Levels, flying uncrewed aircraft into the gloop and releasing charge. Their findings, published in Geophysical Research Letters, showed that when either positive or negative charge was emitted, the fog formed more water droplets.

The findings could be put to good use in dry regions of the world, such as the Middle East and north Africa, as a means of encouraging clouds to release their rain. Cloud droplets are larger than fog droplets and so more likely to collide, and Harrison and his colleagues believe that adding electrical charge to a cloud could help droplets to stick together and become more weighty.
Earth

Toxic Cleanup Technique Can Get More Rare Earth Metals Out of Ores (arstechnica.com) 5

As an added bonus, cleanup after rare earth extraction would be much easier. From a report: A variety of modern technologies, including permanent magnets that have been used in everything from earbuds to wind turbines, rely on rare earth elements. While the metals aren't actually especially rare, they don't occur at high concentrations in the Earth's crust. As such, extracting them is expensive and tends to produce a lot of environmental damage, meaning that most of the supply comes from a small number of countries (see the chart here), leaving the supply at risk of political fights. So the potential to get much more out of existing rare earth mines is obviously very appealing. And the method described in a paper released on Monday seems to offer it all: more metal per ore, much lower cost, and far less worry about mining waste.

Many of the best rare earth deposits occur in places where nature has concentrated the elements for us. These tend to be sediments formed from materials where the rare earth elements will react or interact with the sediment, coming out of solution and gradually building up the concentration in the ore. The usual method of extracting the elements from these ores essentially involves reversing that process. An ion-rich solution is pumped through the ore, and these ions displace the rare earths, allowing them to leach out of the ore. Typically, the solution used is ammonium sulfate. The production of ammonium sulfate has its own energy and materials costs, and it leaves the material behind in the ore, which may require an environmental cleanup afterward. And the process isn't very selective; lots of other, cheaper metals, like aluminum and calcium, also come out of the ore and need to be separated from the desired products.

NASA

SpaceX Is Now Building a Raptor Engine a Day, NASA Says (arstechnica.com) 140

An anonymous reader quotes a report from Ars Technica: A senior NASA official said this week that SpaceX has done "very well" in working toward the development of a vehicle to land humans on the surface of the Moon, taking steps to address two of the space agency's biggest concerns. NASA selected SpaceX and Starship for its Human Landing System in April 2021. In some ways, this was the riskiest choice of NASA's options because Starship is a very large and technically advanced vehicle. However, because of the company's self-investment of billions of dollars into the project, SpaceX submitted the lowest bid, and from its previous work with SpaceX, NASA had confidence that the company would ultimately deliver.

Two of NASA's biggest technological development concerns were the new Raptor rocket engine and the transfer and storage of liquid oxygen and methane propellant in orbit, said Mark Kirasich, NASA's deputy associate administrator who oversees the development of Artemis missions to the Moon. During a subcommittee meeting of NASA's Advisory Council on Monday, however, Kirasich said SpaceX has made substantial progress in both areas. The Raptor rocket engine is crucial to Starship's success. Thirty-three of these Raptor 2 engines power the Super Heavy booster that serves as the vehicle's first stage, and six more are used by the Starship upper stage. For a successful lunar mission, these engines will need to re-light successfully on the surface of the Moon to carry astronauts back to orbit inside Starship. If the engines fail, the astronauts will probably die.

"SpaceX has moved very quickly on development," Kirasich said about Raptor. "We've seen them manufacture what was called Raptor 1.0. They have since upgraded to Raptor 2.0 that first of all increases performance and thrust and secondly reduces the amount of parts, reducing the amount of time to manufacture and test. They build these things very fast. Their goal was seven engines a week, and they hit that about a quarter ago. So they are now building seven engines a week."

Medicine

CVS, Walgreens To Pay More Than $10 Billion To Settle Opioid Lawsuits (wsj.com) 55

CVS and Walgreens have agreed to pay more than $10 billion in a landmark settlement to resolve opioid-crisis lawsuits brought by states, cities and other governments. From a report: The two largest U.S. drugstore chains said they reached a framework to settle the collection of lawsuits brought by governments and Native American tribes blaming pharmacies for helping fuel the nation's opioid epidemic. Under the proposed deal, CVS would pay $4.9 billion to states and municipalities and $130 million to tribes over the next 10 years starting in 2023. The company said the agreement isn't an admission of guilt and that it would continue to defend against any litigation that the settlement doesn't resolve.

Walgreens said it has offered to pay up to $4.79 billion to states over 15 years and about $155 million to tribes. It also expects to pay up to $753.5 million in attorneys fees over six years. The company said the settlement wasn't an admission of wrongdoing. Each state, local government and tribe still must decide whether to participate in the settlement. Plaintiffs' attorneys appointed to lead the negotiations said they encouraged governments and tribes to join the settlement, which they said holds the pharmacies accountable. CVS Chief Executive Karen Lynch, on a call with analysts, said the settlement is in the "best interests of all parties and helps put a decades-old issue behind us." CVS has been in a separate legal battle with its insurers over whether they should cover some of the liability the company faces for the opioid lawsuits.

Space

Black Holes Can Behave Like Quantum Particles (space.com) 42

Black holes have properties characteristic of quantum particles, a new study reveals, suggesting that the puzzling cosmic objects can be at the same time small and big, heavy and light, or dead and alive, just like the legendary Schrodinger's cat. Space.com reports: The new study, based on computer modeling, aimed to find the elusive connection between the mind-boggling time-warping physics of supermassive objects such as black holes and the principles guiding the behavior of the tiniest subatomic particles. The study team developed a mathematical framework that placed a simulated quantum particle just outside a giant simulated black hole. The simulation revealed that the black hole showed signs of quantum superposition, the ability to exist in multiple states at once -- in this case, to be at the same time both massive and not massive at all.

The best known example of quantum superposition is the legendary SchrÃdinger's cat, a thought experiment designed by early 20th century physicist Erwin Schrodinger to demonstrate some of the key issues with quantum physics. According to quantum theories, subatomic particles exist in multiple states simultaneously until they interact with the external world. This interaction, which could be the simple act of being measured or observed, throws the particle into one of the possible states. Schrodinger, who won the Nobel Prize in Physics in 1933, intended the experiment to demonstrate the absurdity of quantum theory, as it would suggest that a cat locked in a box can be at the same time dead and alive based on the random behavior of atoms, until an observer breaks the superposition. However, as it turned out, while a cat in a box could be dead regardless of the observer's actions, a quantum particle may indeed exist in a double state. And the new study indicates that a black hole does as well.
The new study was published online in the journal Physical Review Letters on Friday.
Space

SpaceX Launches First Falcon Heavy Mission in Three Years (reuters.com) 32

SpaceX's Falcon Heavy, the world's most-powerful active rocket, lifted off for the first time in more than three years on Monday from Florida's Cape Canaveral, with Elon Musk's company sending a group of satellites into orbit for the U.S. Space Force. From a report: The rocket system, representing three Falcon 9 boosters strapped side-by-side, lifted off at a SpaceX launch pad. The rocket's two side boosters were due to land in synchrony on adjacent concrete slabs along Florida's east coast roughly eight minutes after liftoff.
Space

Scientists Find Potentially Hazardous Asteroid Hiding In the Sun's Glare (gizmodo.com) 37

A team of researchers has detected a trio of near-Earth asteroids in the inner solar system, one of which is the largest found since 2014 that poses a potential risk to the planet. The asteroids remained undetected until now because they occupy a region of the sky hidden by the Sun's glare. Gizmodo reports: Near-Earth Asteroids (NEAs) and Potentially Hazardous Asteroids (PHAs) are two types of near-Earth objects that space agencies like to keep track of. Despite the scary-sounding names, none of them pose any imminent threat to us. Currently, there are 1,454 NEAs that have a non-zero probability of impacting Earth in the next 100 years. You can find a complete list of NEOs at NASA's Center for Near Earth Object Studies.

The three near-Earth asteroids were found using the Dark Energy Camera in Chile. The camera took deep-field images close to Earth's horizon during twilight, to combat the Sun's glare and atmospheric distortions. The team's results are published in The Astronomical Journal. Two of the recently observed asteroids have orbits that safely skirt Earth, but one of the rocks -- a 0.93-mile-wide (1.5-kilometer) asteroid dubbed 2022 AP7 -- has an orbit that may eventually put it on a collision course with Earth. To be perfectly clear: The asteroid is not currently barreling toward Earth, but its path could bring it close enough one day that NASA will want to keep tabs on it.

China

China Launches Final Module To Complete Tiangong Space Station (space.com) 18

The third and final module has arrived at China's Tiangong space station. Space.com reports: The Mengtian module launched to Earth orbit atop a Long March 5B heavy-lift rocket from Wenchang, south China, at 3:37 a.m. EDT (0737 GMT and 3:37 p.m Beijing time) on Monday (Oct. 31), according to the state-run outlet Xinhua News. Mengtian arrived at Tiangong as planned about 13 hours after liftoff, according to the China Manned Space Agency. The launch marked China's ninth space station-related mission since sending the Tianhe core module into orbit in April last year.

Mengtian, whose name means "Dreaming of the Heavens," is a 58.7-foot-long (17.9 meters) and roughly 48,500-pound (22 metric tons) spacecraft designed mainly to host an array of science racks and experiments. Equipment installed on board Mengtian will be used for experiments related to microgravity, fluid physics, materials science, combustion science, fundamental physics and more. The docking of Mengtian with Tiangong marks the end of the space station's assembly phase and the start of full operations, Chinese space officials have said. Mengtian's arrival allows China to realize a vision for a space station approved way back in 1992.

The Tiangong space station consists of Tianhe, Mengtian and a module called Wentian. The T-shaped Tiangong will host three astronauts for six months at a time, or six crew members for a brief time during crew handovers. Tiangong's first crew handover is expected before the end of the year when the ongoing Shenzhou 14 mission astronauts welcome aboard the new Shenzhou 15 crew, who will launch on a Long March 2F rocket from the Gobi Desert. Ahead of this, China will launch the Tianzhou 5 cargo mission to Tiangong in November to deliver supplies to support the new crew expedition. [...] The space station will also support a powerful survey space telescope named Xuntian that China plans to launch as soon as late 2023. The Hubble-class observatory will operate in a similar orbit to that of Tiangong, meaning it will be able to dock at the station for refueling, upgrades and repairs. Meanwhile, China's first astronaut, Yang Liwei, said earlier this year that Tiangong could be opened to tourism in the future.

Medicine

Former World Chess Champion Anatoly Karpov Hospitalized In Serious Condition 67

According to Russian telegram channels, the former World Chess Champion, Antoly Karpov, was "rushed to the hospital with multiple head injuries in which he was placed in an induced coma," reports ChessBase. "Karpov was put on a ventilator now, and has been diagnosed with cerebral edema, fractures of the right parietal and right temporal bones, multiple head hematomas, and traumatic subarachnoid hemorrhage." From the report: On a few things none of the reports still in circulation disagree: the 12th World Champion and current member of Duma, Anatoly Karpov, 71, was found on the ground outside of the Duma, and unresponsive. His blood alcohol levels were very elevated, and he was rushed to the hospital into intensive care. Some early reports claimed he was the victim of an assault and in induced coma. This was later reiterated by other outlets such as Marca from Spain.

The source of this, according to Tass, Andrei Kovalev, chairman of the All-Russian Movement of Entrepreneurs, announced in his Telegram channel that Karpov was in intensive care after an attack by unknown people and put into an artificial coma. However Karpov's assistant denied this and said he was fine, had no injuries and was in stable condition. Which begs the question, how fine can he be if there is a need to reassure others he is in 'stable condition'. Since Russian media is under very tight control by the Russian State, it is impossible to know where the truth really lies.
Developing...
Math

Why Mathematicians Study Knots (quantamagazine.org) 19

Far from being an abstract mathematical curiosity, knot theory has driven many findings in math and beyond. Quanta magazine: Knot theory began as an attempt to understand the fundamental makeup of the universe. In 1867, when scientists were eagerly trying to figure out what could possibly account for all the different kinds of matter, the Scottish mathematician and physicist Peter Guthrie Tait showed his friend and compatriot Sir William Thomson his device for generating smoke rings. Thomson -- later to become Lord Kelvin (namesake of the temperature scale) -- was captivated by the rings' beguiling shapes, their stability and their interactions. His inspiration led him in a surprising direction: Perhaps, he thought, just as the smoke rings were vortices in the air, atoms were knotted vortex rings in the luminiferous ether, an invisible medium through which, physicists believed, light propagated.

Although this Victorian-era idea may now sound ridiculous, it was not a frivolous investigation. This vortex theory had a lot to recommend it: The sheer diversity of knots, each slightly different, seemed to mirror the different properties of the many chemical elements. The stability of vortex rings might also provide the permanence that atoms required. Vortex theory gained traction in the scientific community and inspired Tait to begin tabulating all knots, creating what he hoped would be equivalent to a table of elements. Of course, atoms are not knots, and there is no ether. By the late 1880s Thomson was gradually abandoning his vortex theory, but by then Tait was captivated by the mathematical elegance of his knots, and he continued his tabulation project. In the process, he established the mathematical field of knot theory.

We are all familiar with knots -- they keep shoes on our feet, boats secured to docks, and mountain climbers off the rocks below. But those knots are not exactly what mathematicians (including Tait) would call a knot. Although a tangled extension cord may appear knotted, it's always possible to disentangle it. To get a mathematical knot, you must plug together the free ends of the cord to form a closed loop. Because the strands of a knot are flexible like string, mathematicians view knot theory as a subfield of topology, the study of malleable shapes. Sometimes it is possible to untangle a knot so it becomes a simple circle, which we call the "unknot." But more often, untangling a knot is impossible.

Space

Behavior of Star Clusters Challenges Newton's Laws of Gravity (jpost.com) 90

The Jerusalem Post reports that "Certain star clusters do not seem to be following current understandings of Isaac Newton's laws of gravity, according to new research published on Wednesday." (Specifically open star clusters, formed when thousands of stars are born in a gas cloud within a short time period.)

The researchers examined data on each stars' velocity, direction of motion and age using data from the European Space Agency's Gaia mission that allowed them to count the stars accurately for the very first time. The results? As the clusters dissolve, the stars accumulate on two "tidal tails:" one pulled behind the cluster and the other pushed forward. "According to Newton's laws of gravity, it's a matter of chance in which of the tails a lost star ends up," explains Dr. Jan Pflamm-Altenburg of the Helmholtz Institute of Radiation and Nuclear Physics at the University of Bonn. "So both tails should contain about the same number of stars. However, in our work we were able to prove for the first time that this is not true: In the clusters we studied, the front tail always contains significantly more stars nearby to the cluster than the rear tail...."

When the researchers looked at the data, they found that it did not fit Newton's law of gravity and instead fit better with an alternate theory called Modified Newtonian Dynamics (MOND).

"Put simply, according to MOND, stars can leave a cluster through two different doors," explained Prof. Dr. Pavel Kroupa of the Helmholtz Institute of Radiation and Nuclear Physics. "One leads to the rear tidal tail, the other to the front. However, the first is much narrower than the second — so it's less likely that a star will leave the cluster through it. Newton's theory of gravity, on the other hand, predicts that both doors should be the same width...."

The simulations also coincided with the Gaia data in terms of how long the star clusters typically survive, which is much shorter than would be expected according to Newton's laws....

The MOND theory is controversial as modifications to Newton's laws of gravity would have far-reaching consequences for other areas of physics as well, although they would solve many problems facing cosmology.

Thanks to long-time Slashdot reader schwit1 for submitting the story!
Medicine

'Science Has a Nasty Photoshopping Problem' (nytimes.com) 190

Dr. Bik is a microbiologist who has worked at Stanford University and for the Dutch National Institute for Health who is "blessed" with "what I'm told is a better-than-average ability to spot repeating patterns," according to their new Op-Ed in the New York Times.

In 2014 they'd spotted the same photo "being used in two different papers to represent results from three entirely different experiments...." Although this was eight years ago, I distinctly recall how angry it made me. This was cheating, pure and simple. By editing an image to produce a desired result, a scientist can manufacture proof for a favored hypothesis, or create a signal out of noise. Scientists must rely on and build on one another's work. Cheating is a transgression against everything that science should be. If scientific papers contain errors or — much worse — fraudulent data and fabricated imagery, other researchers are likely to waste time and grant money chasing theories based on made-up results.....

But were those duplicated images just an isolated case? With little clue about how big this would get, I began searching for suspicious figures in biomedical journals.... By day I went to my job in a lab at Stanford University, but I was soon spending every evening and most weekends looking for suspicious images. In 2016, I published an analysis of 20,621 peer-reviewed papers, discovering problematic images in no fewer than one in 25. Half of these appeared to have been manipulated deliberately — rotated, flipped, stretched or otherwise photoshopped. With a sense of unease about how much bad science might be in journals, I quit my full-time job in 2019 so that I could devote myself to finding and reporting more cases of scientific fraud.

Using my pattern-matching eyes and lots of caffeine, I have analyzed more than 100,000 papers since 2014 and found apparent image duplication in 4,800 and similar evidence of error, cheating or other ethical problems in an additional 1,700. I've reported 2,500 of these to their journals' editors and — after learning the hard way that journals often do not respond to these cases — posted many of those papers along with 3,500 more to PubPeer, a website where scientific literature is discussed in public....

Unfortunately, many scientific journals and academic institutions are slow to respond to evidence of image manipulation — if they take action at all. So far, my work has resulted in 956 corrections and 923 retractions, but a majority of the papers I have reported to the journals remain unaddressed.

Manipulated images "raise questions about an entire line of research, which means potentially millions of dollars of wasted grant money and years of false hope for patients." Part of the problem is that despite "peer review" at scientific journals, "peer review is unpaid and undervalued, and the system is based on a trusting, non-adversarial relationship. Peer review is not set up to detect fraud."

But there's other problems. Most of my fellow detectives remain anonymous, operating under pseudonyms such as Smut Clyde or Cheshire. Criticizing other scientists' work is often not well received, and concerns about negative career consequences can prevent scientists from speaking out. Image problems I have reported under my full name have resulted in hateful messages, angry videos on social media sites and two lawsuit threats....

Things could be about to get even worse. Artificial intelligence might help detect duplicated data in research, but it can also be used to generate fake data. It is easy nowadays to produce fabricated photos or videos of events that never happened, and A.I.-generated images might have already started to poison the scientific literature. As A.I. technology develops, it will become significantly harder to distinguish fake from real.

Science needs to get serious about research fraud.

Among their proposed solutions? "Journals should pay the data detectives who find fatal errors or misconduct in published papers, similar to how tech companies pay bounties to computer security experts who find bugs in software."
Medicine

The World Is Running Out of Helium. Why Doctors are Worried (nbcnews.com) 130

NBC News reports: A global helium shortage has doctors worried about one of the natural gas's most essential, and perhaps unexpected, uses: MRIs.

Strange as it sounds, the lighter-than-air element that gives balloons their buoyancy also powers the vital medical diagnostic machines. An MRI can't function without some 2,000 liters of ultra-cold liquid helium keeping its magnets cool enough to work. But helium — a nonrenewable element found deep within the Earth's crust — is running low, leaving hospitals wondering how to plan for a future with a much scarcer supply.... [F]our of five major U.S. helium suppliers are rationing the element, said Phil Kornbluth, president of Kornbluth Helium Consulting. These suppliers are prioritizing the health care industry by reducing helium allotments to less essential customers.

Hospitals haven't canceled patients' MRIs or shut down machines yet. They have seen helium costs rise at an alarming rate, though — possibly up to 30%, guessed Phil Kornbluth, president of Kornbluth Helium Consulting. But without an end in sight for the helium shortage, the future of MRI remains uncertain.... The problem is that no other element is cold enough for the MRI. "There's no alternative," said Donna Craft, a regional construction manager for Premier Inc. who contracts with helium suppliers for some 4,000 hospitals. "Without helium, MRIs would have to shut down...."

GE and Siemens are both developing MRIs requiring less liquid helium. Siemens recently introduced one requiring just 0.7 liters, and, according to Panagiotelis, GE rolled out a machine that's "1.4 times more efficient than previous models." These technologies aren't widely available, though, and replacing the country's 12,000 MRI machines — each weighing up to 50,000 pounds — is anything but a quick fix. Meanwhile, hospitals keep installing additional conventional MRI machines to meet demand for diagnostic scans.

The article notes some scientists are already shutting down research projects that require helium.

Thanks to long-time Slashdot reader Wildbear for submitting the article!

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