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Science

CDC Expresses Concern About Possibility of Undetected Monkeypox Spread in UK (statnews.com) 30

The Centers for Disease Control and Prevention has expressed concern about an unusual outbreak of monkeypox in the United Kingdom, suggesting there appears to be at least some undetected transmission of the virus there and warning of the possibility that the outbreak could spread beyond U.K. borders. From a report: "We do have a level of concern that this is very different than what we typically think of from monkeypox. And I think we have some concern that there could be spread outside the U.K associated with this," Jennifer McQuiston, a senior CDC official, told STAT in an interview.

Seven confirmed and one probable case of monkeypox have been discovered in the U.K. since early May -- an unusually large number given that human monkeypox cases are uncommon, and are especially rare outside West and Central Africa. While one of the cases had recently traveled to Nigeria, where monkeypox is endemic, the others appear to have contracted the virus in the U.K. None of the people infected domestically has any known connections with the traveler and the timing of the onset of the cases suggest he was not the source of those infections.
Further reading: Spain, Portugal report monkeypox cases, raising specter of wider outbreak.
Science

Who Owns Einstein? The Battle For the World's Most Famous Face 58

During his lifetime, Einstein resisted the attempts to commercialise his identity. Now someone makes more than $12 million a year on image licensing. Even the law that allows this profiteering is contentious. Can an heir inherit rights that did not yet exist during the originator's lifetime? More on this on a long read from The Guardian.
Medicine

Contact Lens That Can Release Drug Could Be Used To Treat Glaucoma (theguardian.com) 12

An anonymous reader quotes a report from The Guardian: Researchers in China revealed they have developed a contact lens that can sense an increase in pressure within the eye and release an anti-glaucoma drug should the pressure exceed a certain level. Writing in the journal Nature Communications, the team describe how they created the device using an upper and lower lens, with a snowflake-shaped pressure sensor and wireless power transfer device sandwiched between them around the rim of the lenses. The arrangement appears to give the effect of the wearer having golden irises. However, the team say the design allows the necessary components to be included in the device without blocking the wearer's view or irritating the eye.

When the pressure inside the eye increases, the gap between the upper and lower lenses decreases. This is detected by the pressure sensor by means of a cantilever. The sensor then sends a signal to the wireless system which subsequently triggers the release of an anti-glaucoma drug, from a hydrogel attached to an electrode, and enables it to cross the cornea of the eye. The drug, brimonidine, acts to reduce the pressure within the eye. The study reveals that the contact lenses have so far been tested on pigs' eyes and on the eyes of living rabbits -- albeit with smaller-sized lenses -- although trials have yet to be carried out in humans. The researchers note the lenses are not only soft and minimally invasive but are also battery-free, adding that the approach could be expanded to help tackle other eye diseases.
"We can now imagine that a glaucoma sufferer wearing these contact lenses will not only receive real-time information about the pressures within the eye, since the contact lens has built-in wireless capacity and can easily communicate with an app on your smartphone, but also receive, for example, pressure-relieving drugs when needed," said Prof Zubair Ahmed from the Institute of Inflammation and Aging at the University of Birmingham. "The materials required to create such contact lenses are inexpensive and soon could be mass-produced," he added.
Medicine

South Korea Turns To Surveillance As 'Ghost Surgeries' Shake Faith In Hospitals (nytimes.com) 71

After scandals in which doctors let unsupervised assistants operate on patients, South Korea is becoming one of the first to require cameras in operating rooms. The New York Times reports: Ethicists and medical officials, including those at the American College of Surgeons, have cautioned that surveilling surgeons to deter malpractice may undermine trust in doctors, hurt morale, violate patient privacy and discourage physicians from taking risks to save lives. The Korea Medical Association, which is opposed to the new mandate, has lobbied to limit its impact. But supporters of the law said the move would help protect patients, build the public's trust in doctors and provide victims of medical malpractice with evidence to use in court.

"People are dying in operating rooms," said An Gi-jong, an advocate for patients. "We can't rely on doctors to solve problems on their own anymore." About five patients have died from ghost surgeries in the past eight years, he said. They include Kwon Dae-hee, a college student in Seoul who died of a hemorrhage in 2016 after jawline surgery. His mother, Lee Na-geum, who obtained footage of his operation and reviewed it hundreds of times, found evidence that the operation had been botched because parts of it had been conducted by an unsupervised nursing assistant. Ms. Lee, 62, who has held a public vigil denouncing ghost surgeries since her son's death, said in an interview: "Once the cameras are installed, your lies will be exposed if you're a ghost doctor. Cameras reveal truth." [...]

Under the new law, hospitals performing surgeries on unconscious patients must install video cameras in their operating rooms. If a patient or a relative requests that a surgery be filmed, the hospital must comply. Doctors can refuse for certain reasons, such as if a delay in the operation would put the patient's life at risk, or if the filming would significantly impede residents' training. The recorded footage can be viewed for criminal investigations, prosecutions, trials, medical disputes or mediation.

United States

US Officials Say Pentagon Committed To Understanding UFO Origins (reuters.com) 75

Two senior U.S. defense intelligence officials said on Tuesday the Pentagon is committed to determining the origins of what it calls "unidentified aerial phenomena" -- commonly termed UFOs -- but acknowledged many remain beyond the government's ability to explain. From a report: The two officials, Ronald Moultrie and Scott Bray, appeared before a House of Representatives intelligence subcommittee for the first public U.S. congressional hearing on the subject in a half century. It came 11 months after a government report documented more than 140 cases of unidentified aerial phenomena, or UAPs, that U.S. military pilots had observed since 2004. Bray, deputy director of naval intelligence, said the number of UAPs officially cataloged by a newly formed Pentagon task force has grown to 400 cases. Both officials chose their words carefully in describing the task force's work, including the question of possible extraterrestrial origins, which Bray said defense and intelligence analysts had not ruled out. Bray did say that "we have no material, we have detected no emanations, within the UAP task force that would suggest it is anything non-terrestrial in origin."
AI

MIT, Harvard Scientists Find AI Can Recognize Race From X-rays (bostonglobe.com) 291

A doctor can't tell if somebody is Black, Asian, or white, just by looking at their X-rays. But a computer can, according to a surprising new paper by an international team of scientists, including researchers at the Massachusetts Institute of Technology and Harvard Medical School. From a report: The study found that an artificial intelligence program trained to read X-rays and CT scans could predict a person's race with 90 percent accuracy. But the scientists who conducted the study say they have no idea how the computer figures it out. "When my graduate students showed me some of the results that were in this paper, I actually thought it must be a mistake," said Marzyeh Ghassemi, an MIT assistant professor of electrical engineering and computer science, and coauthor of the paper, which was published Wednesday in the medical journal The Lancet Digital Health. "I honestly thought my students were crazy when they told me."

At a time when AI software is increasingly used to help doctors make diagnostic decisions, the research raises the unsettling prospect that AI-based diagnostic systems could unintentionally generate racially biased results. For example, an AI (with access to X-rays) could automatically recommend a particular course of treatment for all Black patients, whether or not it's best for a specific person. Meanwhile, the patient's human physician wouldn't know that the AI based its diagnosis on racial data.

Mars

After 28 Flights, Is NASA's 'Ingenuity' Mars Helicopter Nearing the End of Its Life? (msn.com) 61

After traveling 300 miles on the underbelly of the Perseverance rover, the "Ingenuity" helicopter has made 28 different flights over the surface of Mars, reports the Washington Post, staying aloft for a total of nearly one hour, flying 4.3 miles with a maximum speed of 12.3 miles per hour and a top altitude of 39 feet. "It's traversed craters, taken photos of regions that would be hard to reach on the ground, and served as a surprisingly resilient scout that has adapted to the changing Martian atmosphere and survived its harsh dust storms and frigid nights.

"Now the engineers and scientists at NASA's Jet Propulsion Laboratory are worried that their four-pound, solar-powered drone on Mars, may be nearing the end of its life." Winter is setting in on Mars. The dust is kicking up, coating Ingenuity's solar panels and preventing it from fully charging its six lithium-ion batteries. This month, for the first time since it landed on Mars more than a year ago, Ingenuity missed a planned communications session with Perseverance, the Mars rover that it relies on to send data and receive commands from Earth. Will a dust-coated Ingenuity survive a Martian winter where temperatures routinely plunge below minus-100 degrees Fahrenheit? And if it doesn't, how should the world remember the little helicopter that cost $80 million to develop and more than five years to design and build? Those closest to the project say that as time winds down for Ingenuity, it's hard to overstate its achievements....

"We built it as an experiment," Lori Glaze, the director of NASA's planetary science division, told The Washington Post. "So it didn't necessarily have the flight-qualified parts that we use on the big missions like Perseverance." Some, such as components from smartphones, were even bought off-the-shelf, so "there were chances that they might not perform in the environment as we expected. And so there was a risk that it wasn't going to work.... What happened was, and this is really key, after Ingenuity performed so well on those first five flights, the science team from Perseverance came to us and said, 'You know what, we want this helicopter to keep operating to help us in our exploration and achieving our science goals,' " Glaze said.

So NASA decided to keep flying....

On April 29, it took its last flight to date, No. 28, a quarter-of-a-mile jaunt that lasted two-and-a-half minutes. Now NASA wonders if that will be the last one. The space agency thinks the helicopter's inability to fully charge its batteries caused the helicopter to enter a low-power state. When it went dormant, the helicopter's onboard clock reset, the way household clocks do after a power outage. So the next day, as the sun rose and began to charge the batteries, the helicopter was out of sync with the rover: "Essentially, when Ingenuity thought it was time to contact Perseverance, the rover's base station wasn't listening," NASA wrote.

Then NASA did something extraordinary: Mission controllers commanded Perseverance to spend almost all of May 5 listening for the helicopter.

Finally, little Ingenuity phoned home.

The radio link, NASA said, "was stable," the helicopter was healthy, and the battery was charging at 41 percent.

But, as NASA warned, "one radio communications session does not mean Ingenuity is out of the woods. The increased (light-reducing) dust in the air means charging the helicopter's batteries to a level that would allow important components (like the clock and heaters) to remain energized through the night presents a significant challenge."

Maybe Ingenuity will fly again. Maybe not.

"At this point, I can't tell you what's going to happen next," Glaze said. "We're still working on trying to find a way to fly it again. But Perseverance is the primary mission, so that we need to start setting our expectations appropriately."

For Ingenuity's "Wright Brothers moment" — when it flew for the first time on another planet — it was actually carrying a postage-sized bit of fabric from the Wright Brothers original 1903 aircraft.
Medicine

Promising Early Results From Largest-Ever Trial Testing LSD For Anxiety 66

Biopharmaceutical company MindMed has announced the first topline data from a novel Phase 2 trial testing high doses of LSD as a treatment for anxiety. The results indicate one to two LSD sessions can generate rapid and sustained reductions to anxiety, however, significantly larger trials will be needed to validate these findings. New Atlas reports: This new trial was conducted at University Hospital Basel in Switzerland. The trial was randomized, and placebo-controlled with a crossover design enrolling 46 participants. The participants completed two high-dose (200-microgram) LSD sessions, six weeks apart. The primary endpoint was a reduction in anxiety 16 weeks after the second LSD session, as measured on a scale called STAI (State-Trait Anxiety Inventory), a common test used to quantify anxiety.

The data revealed by MindMed indicates 65 percent (13 out of 20) patients in the LSD group demonstrated a clinically significant reduction in STAI scores of more than 30 percent. Only nine percent of the placebo group (two out of 22) showed similar clinical improvements. The results indicate the treatment was generally safe with only mild adverse effects reported by most subjects. The announcement did report one serious adverse treatment event during an LSD session described as "acute transient anxiety and delusions." This subject required sedatives but no long-term adverse effects were noted. [...] MindMed is now beginning a Phase 2b trial to expand on these findings and further explore LSD as a treatment for anxiety disorders.
Space

Virgin Orbit Is Assembling a Fleet of Boeing 747 Jets To Launch More Rockets Into Space (cnbc.com) 30

Virgin Orbit is assembling a fleet of modified 747 jets, the company announced Tuesday, ordering two new modified cargo airframes to help launch more rockets into space. CNBC reports: The company is acquiring the two additional airframes through L3Harris, which will modify the jets to carry and launch Virgin Orbit's rockets. Virgin expects to take delivery of the first of the planes next year. Virgin Orbit CEO Dan Hart said the delivery timing of the second plane will be "driven more by market demand" for launches. The deal "unleashes us in a few ways," he said. "It eliminates one of the key chokepoints that we have in the system," Hart told CNBC. It also will help the company keep launches going in case one of their aircraft is undergoing maintenance, which will open up "all sorts of possibilities for supporting different customers in different places," he added.

Virgin Orbit has a single aircraft, a customized Boeing 747-400 called "Cosmic Girl," which has flown four missions of Virgin Orbit's LauncherOne rocket to date. Through a method known as air launch, the company's aircraft carries its rockets to about 45,000 feet of altitude and drops them just before they fire their engines and accelerate into space -- a method the company touts as more flexible than ground-based systems. [...] Virgin Orbit's new 747s will also feature an improved layout, with L3Harris modifying the aircraft to carry up to two LauncherOne rockets, as well as all of the company's ground support equipment, to a launch site.

Moon

Cress Seeds Grown in Moon Dust Raise Hopes for Lunar Crops (theguardian.com) 34

The prospect of growing crops on the moon has edged a little closer after researchers nurtured plants -- some more successfully than others -- in lunar soil for the first time. From a report: Scientists planted thale cress seeds in moon dust brought back by three Apollo missions and watched them sprout and grow into fully fledged plants, raising the potential for astronauts to farm off-world crops. But while the plants survived in the lunar soil, or regolith, they fell short of thriving, growing more slowly than cress planted in volcanic ash, developing stunted roots, and showing clear signs of physiological stress.

"We found that plants do indeed grow in lunar regolith, however they respond as if they are growing in a stressful situation," said Dr Anna-Lisa Paul, a molecular biologist at the University of Florida. Thale cress, or Arabidopsis thaliana, is a small flowering plant related to broccoli, cauliflower and kale. "It's not especially tasty," Paul added. The experiments are the first to investigate whether plants can grow in lunar soil and follow an 11-year effort to obtain the rare material. Because the soil is so precious, Nasa loaned only 12g of it -- a few teaspoons -- to the researchers who conducted the tests. Scientists have long wondered whether the moon could support crops, but with space agencies now planning to return humans to the surface, and potentially build lunar settlements for visitors, the question has become more pressing.

Space

The Milky Way's Black Hole Comes to Light (nytimes.com) 65

Astronomers announced today that they had pierced the veil of darkness and dust at the center of our Milky Way galaxy to capture the first picture of "the gentle giant" dwelling there: A supermassive black hole, a trapdoor in space-time through which the equivalent of 4 million suns have been dispatched to eternity, leaving behind only their gravity and a violently bent space-time. From a report: The image, released in six simultaneous news conferences in Washington, D.C., and around the globe, showed a lumpy doughnut of radio emission framing an empty space as dark and silent as death itself. The new image joins the first ever picture of a black hole, produced in 2019 by the same team, which photographed the monster at the heart of the M87. The new image shows new details of the astrophysical violence and gravitational weirdness holding sway at the center of our placid-looking hive of starlight.

Black holes were an unwelcome consequence of Albert Einstein's general theory of relativity, which attributes gravity to the warping of space and time by matter and energy, much as a mattress sags under a sleeper. Einstein's insight led to a new conception of the cosmos, in which space-time could quiver, bend, rip, expand, swirl and even disappear forever into the maw of a black hole, an entity with gravity so strong that not even light could escape it. Einstein disapproved of this idea, but the universe is now known to be speckled with black holes. Many are the remains of dead stars that collapsed inward on themselves and just kept going. But there seems to be a black hole at the center of nearly every galaxy, ours included, that can be millions or billions of times as massive than our sun. Astronomers still do not understand how these supermassive black holes have grown so big.

Medicine

Blocking Inflammation May Lead To Chronic Pain (neurosciencenews.com) 128

Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from McGill University and colleagues in Italy. Neuroscience News reports: Their research puts into question conventional practices used to alleviate pain. Normal recovery from a painful injury involves inflammation and blocking that inflammation with drugs could lead to harder-to-treat pain. [...] In the study published in Science Translational Medicine, the researchers examined the mechanisms of pain in both humans and mice. They found that neutrophils -- a type of white blood cell that helps the body fight infection -- play a key role in resolving pain. Experimentally blocking neutrophils in mice prolonged the pain up to ten times the normal duration. Treating the pain with anti-inflammatory drugs and steroids like dexamethasone and diclofenac also produced the same result, although they were effective against pain early on.

These findings are also supported by a separate analysis of 500,000 people in the United Kingdom that showed that those taking anti-inflammatory drugs to treat their pain were more likely to have pain two to ten years later, an effect not seen in people taking acetaminophen or anti-depressants. "Our findings suggest it may be time to reconsider the way we treat acute pain. Luckily pain can be killed in other ways that don't involve interfering with inflammation," says Massimo Allegri, a Physician at the Policlinico of Monza Hospital in Italy and Ensemble Hospitalier de la Cote in Switzerland.

Science

Unusual Quantum State of Matter Observed For the First Time (phys.org) 17

An anonymous reader quotes a report from Phys.Org: It's not every day that someone comes across a new state of matter in quantum physics, the scientific field devoted to describing the behavior of atomic and subatomic particles in order to elucidate their properties. Yet this is exactly what an international team of researchers that includes Andrea Bianchi, University of Montreal physics professor and researcher at the Regroupement quebecois sur les materiaux de pointe, and his students Avner Fitterman and Jeremi Dudemaine has done. In a recent article published in the scientific journalPhysical Review X, the researchers document a "quantum spin liquid ground state" in a magnetic material created in Bianchi's lab: Ce2Zr2O7, a compound composed of cerium, zirconium and oxygen. In quantum physics, spin is an internal property of electrons linked to their rotation. It is spin that gives the material in a magnet its magnetic properties.
[...]
Ce2Zr2O7 is a cerium-based material with magnetic properties. "The existence of this compound was known," said Bianchi. "Our breakthrough was creating it in a uniquely pure form. We used samples melted in an optical furnace to produce a near-perfect triangular arrangement of atoms and then checked the quantum state." It was this near-perfect triangle that enabled Bianchi and his team at UdeM to create magnetic frustration in Ce2Zr2O7. Working with researchers at McMaster and Colorado State universities, Los Alamos National Laboratory and the Max Planck Institute for the Physics of Complex System in Dresden, Germany, they measured the compound's magnetic diffusion. "Our measurements showed an overlapping particle function -- therefore no Bragg peaks -- a clear sign of the absence of classical magnetic order," said Bianchi. "We also observed a distribution of spins with continuously fluctuating directions, which is characteristic of spin liquids and magnetic frustration. This indicates that the material we created behaves like a true spin liquid at low temperatures." After corroborating these observations with computer simulations, the team concluded that they were indeed witnessing a never-before-seen quantum state.

Earth

Scientists Discover Unexplained Abundance of Rare Nuclear Fusion Fuel on Earth (vice.com) 87

An anonymous reader quotes a report from Motherboard: Scientists have discovered evidence that a key rare resource, called helium-3, is potentially ten times more common on Earth than previously known -- though the source of all this extra supply remains mysterious, reports a new study. The finding is important because helium-3 could serve as a foundation of limitless clean power for our civilization, but has been seen as inaccessible since it is largely found in outer space locations, especially the Moon. Helium-3 is an isotope of helium, which means it contains the same number of protons as this common element but a different number of neutrons. This isotope is considered a potentially powerful energy source for future fusion reactors, making it a star of science fiction as well as a sought-out resource in the real world. However, while small amounts of the substance are produced by geological processes and from the fallout of nuclear weapons testing, there is thought to be very little helium-3 available on Earth.

Now, scientists led by Benjamin Birner, a postdoctoral scholar in geosciences at the University of California San Diego, have captured evidence for a previously unknown abundance of helium-3 in the atmosphere, which "presents a major puzzle in the helium-3 budget" and "motivates a search for missing helium-3 sources on Earth, especially since helium-3 is considered an important, yet scarce, resource," according to a study published on Monday in Nature Geoscience. Known sources of helium-3 on Earth only account for 10 percent of the surplus, the researchers said. Birner and his colleagues serendipitously uncovered this inferred surplus of helium-3 (3He) while tackling another challenging problem: measuring the overall rise in atmospheric helium as a result of human consumption of fossil fuels. The team pioneered a first-of-its-kind technique for estimating these anthropogenic helium emissions by examining another isotope, helium-4 (4He), which in turn led to the perplexing conclusion that there is some unknown source of helium-3 on our planet. "We only measured the change in atmospheric 4He," Birner said in an email. "However, previous work by other researchers indicates that the helium isotopic ratio of the atmosphere (3He/4He) is roughly stable. Together these observations imply an increase in atmospheric 3He that matches the rise in 4He or we would see a change in the atmospheric isotope ratio."

Helium-3 could be the ideal fuel for nuclear fusion, a potential energy source that mimics the same process that powers stars. Though nuclear fusion may not materialize as a practical power source for decades, assuming it is feasible at all, its potential to provide clean and limitless energy to the global human population makes it a tantalizing area of study. To that end, scientists across fields are likely to be interested in locating this unexplained surplus of helium-3 on Earth that has been implied by the new research. "That increase of 3He is quite puzzling because we don't have a good explanation for the source of this 3He so far," Birner noted. "It's quite an important puzzle to solve also because 3He is an important and scarce resource for nuclear fusion reactors. Based on the reported uncertainties in previous studies of the atmospheric 3He/4He trend, the buildup of 3He looks significant, but our study clearly motivates a closer look at the atmospheric 3He/4He trend."

Earth

Scientists Give Earth a 50-50 Chance of Hitting Key Warming Mark By 2026 (npr.org) 202

The world is creeping closer to the warming threshold international agreements are trying to prevent, with nearly a 50-50 chance that Earth will temporarily hit that temperature mark within the next five years, teams of meteorologists across the globe predicted. NPR reports: With human-made climate change continuing, there's a 48% chance that the globe will reach a yearly average of 1.5 degrees Celsius (2.7 degrees Fahrenheit) above pre-industrial levels of the late 1800s at least once between now and 2026, a bright red signal in climate change negotiations and science, a team of 11 different forecast centers predicted for the World Meteorological Organization late Monday. The odds are inching up along with the thermometer. Last year, the same forecasters put the odds at closer to 40% and a decade ago it was only 10%.

The team, coordinated by the United Kingdom's Meteorological Office, in their five-year general outlook said there is a 93% chance that the world will set a record for hottest year by the end of 2026. They also said there's a 93% chance that the five years from 2022 to 2026 will be the hottest on record. Forecasters also predict the devastating fire-prone megadrought in the U.S. Southwest will keep going. "We're going to see continued warming in line with what is expected with climate change," said UK Met Office senior scientist Leon Hermanson, who coordinated the report.

Earth

The Ocean Is Starting To Lose Its Memory, Scientists Warn (sciencealert.com) 70

An anonymous reader quotes a report from ScienceAlert: The oceans that surround us are transforming. As our climate changes, the world's waters are shifting too, with abnormalities evident not only in the ocean's temperature, but also its structure, currents, and even its color. As these changes manifest, the usually stable environment of the ocean is becoming more unpredictable and erratic, and in some ways the phenomenon is akin to the ocean losing its memory, scientists suggest. "Ocean memory, the persistence of ocean conditions, is a major source of predictability in the climate system beyond weather time scales," researchers explain in a new paper led by first author and climate researcher Hui Shi from the Farallon Institute in Petaluma, California. "We show that ocean memory, as measured by the year-to-year persistence of sea surface temperature anomalies, is projected to steadily decline in the coming decades over much of the globe."

In the research, the team studied sea surface temperatures (SSTs) in the shallow top layer of the ocean, called the upper-ocean mixed layer (MLD). Despite the MLD's relative shallowness -- extending only to a depth of about 50 meters down from the ocean's surface -- this upper layer of water exhibits a lot of persistence over time in terms of thermal inertia, especially compared to the variations seen in the atmosphere above. In the future, however, modeling suggests that this 'memory' effect of thermal inertia in the upper ocean is set to decline globally over the rest of the century, with dramatically greater variations in temperature predicted over coming decades.

According to the researchers, shoaling effects in the MLD will introduce greater levels of water-mixing in the upper ocean, effectively thinning out the top layer. This is expected to lower the ocean's capacity for thermal inertia, rendering the upper ocean more susceptible to random temperature anomalies. Just what that means for marine wildlife is unclear, but the researchers note that "consequential impacts on populations are likely," although some species are expected to fare better than others in terms of adaptation. On another note, the ocean memory decline is expected to make it significantly harder for scientists to forecast upcoming ocean dynamics, reducing reliable lead times for all sorts of predictions related to SSTs. This will hinder our ability to project monsoons, marine heatwaves (MHWs), and periods of extreme weather, among other things.
The findings have been published in the journal Science Advances.
NASA

NASA Releases Ridiculously Sharp Webb Space Telescope Images (gizmodo.com) 96

During a press conference Monday morning, NASA provided an update on the status of the Webb Space Telescope and released images from the telescope that put Webb's progress on dazzling display. Gizmodo reports: "I'm delighted to report that the telescope alignment has been completed with performance even better than we had anticipated," said Michael McElwain, a Webb observatory project scientist at NASA's Goddard Space Flight Center, in a NASA press conference. "This is an extraordinary milestone for humanity." Webb sits at an observational point called L2 nearly 1 million miles from Earth, where it will look further back in time than the Hubble Space Telescope. (Hubble will continue to operate alongside Webb once the latter is operational). [...] The preparation and testing of the telescope's science instruments (a process called commissioning) will take about two months to complete. Only once the commissioning is complete can Webb begin taking the scientific images that will define its tenure in space.

But some images are already being collected, to make sure the telescope is functioning properly. Webb's coldest instrument -- the Mid-Infrared Instrument (MIRI) -- recently took a test image of the Large Magellanic Cloud, a satellite galaxy of the Milky Way that was previously imaged by the now-retired Spitzer Space Telescope's Infrared Array Camera. Webb's image of the same region makes Spitzer's look like a finger painting, showing interstellar gas clearly distributed across the star field. The stars -- blots, in Spitzer's view -- are seven-pointed beacons of light in the MIRI test.

Webb's next steps will focus on taking images of its science targets, known as early release observations. These will not only be the first images of Webb science targets, but they will be the first images processed into full color. (Webb sees the cosmos in the infrared and near-infrared wavelengths, but the images will be translated into visible light.) Klaus Pontoppidan, a Webb project scientist at the Space Telescope Science Institute, said in the briefing that the chief differences between the most recent images and the ones to come are that the former were taken to test the telescope's ability to see clearly, whereas the latter will test the telescope's ability to image science targets. Pontoppidan wouldn't elaborate on what Webb team will capture in the early release observations -- the targets are a "surprise," he said.

Medicine

Magnets Made By Soil Bacteria Offer Hope For Breast and Prostate Cancer (theguardian.com) 17

An anonymous reader quotes a report from The Guardian: Scientists are developing magnetically guided microscopic projectiles that can be injected into patients' blood to attack breast, prostate and other tumors. The project -- led by researchers at Sheffield University -- builds on progress in two key medical fields. The first involves viruses that specifically attack tumors. The second focuses on soil bacteria that manufacture magnets which they use to align themselves in the Earth's magnetic field.

The anti-cancer viruses that are being exploited by the Sheffield group -- who have been funded by Cancer Research UK -- are known as oncolytic viruses. They occur naturally but can also be modified to improve their efficacy and to limit the chances of them infecting healthy cells. [...] "The problem is that oncolytic viruses attract the attention of the body's immune defenses and only skin-deep tumors can be tackled this way before the viruses are blocked fairly quickly by our cell defenses," said Dr Faith Howard, another project leader. A solution, the scientists say, is to coat the viruses in magnetic particles. Injected into the blood, these microscopic projectiles could then be directed quickly to a tumor -- by using magnets placed over a patient's body -- before their progress can be blocked by immune defenses.

An oncolytic virus had a diameter of about 180 nanometers while the magnets needed to be about 50 nanometers in size, added Howard. (A nanometre is a billionth of a meter.) "These tiny magnets could be made in the laboratory but we have found bacteria do a better job of manufacturing them than we could," she added. Some species of soil bacteria synthesize iron oxide nanoparticles that are called magnetosomes. These are used as compasses that allow the microbes to navigate in Earth's magnetic field and help them find optimum conditions for their growth and survival. "These microscopic magnets they make are perfectly shaped and ideally suited to the microscopic packages we need to target deep cancers," Howard said.

News

Europe's First Psychedelic Drug Trial Firm To Open in London (theguardian.com) 21

Europe's first commercial facility for psychedelic drug trials is to open in London, with the goal of making the UK a global leader in psychedelics research and innovation. From a report: The British startup Clerkenwell Health aims to begin trials in its central London facility in August, initially focusing on the use of psilocybin to help people deal with the anxiety associated with a diagnosis of terminal illness, and to support them through their end-of-life care. The news comes as scientists and policymakers gather in London this Wednesday for the Agenda for Psych Symposium, a daylong programme to discuss the latest research and the future of the psychedelics industry in Europe.
Space

NASA Releases New Black Hole Visualizations - and Sonifications - as Astronomers Study X-Ray Echoes (nasa.gov) 5

NASA has released some surprisingly colorful visualization of black holes. Digital Trends explains their origins: We're coming to the end of Black Hole Week, NASA's celebration of the beastly cosmic monsters which suck in light, matter, and everything else that comes too close to them....

As part of the festivities, the media department at NASA's Goddard Space Flight Center has shared a selection of some of the best visualizations of black holes, so you can get an idea of what these mind-bending phenomena are like. The images, which are also available as desktop and mobile wallpapers should you wish to decorate your devices with black hole imagery, show simulations and visualizations created to try and picture what the weird effects of the extreme gravitational forces around a black hole would be.

NASA describes this as "translating the inherently digital data (in the form of ones and zeroes) captured by telescopes in space into images, [creating] visual representations of what would otherwise be invisible to us."

"But what about experiencing these data with other senses, like hearing?

"Sonification is the process that translates data into sound. Our new project brings parts of our Milky Way galaxy, and of the greater Universe beyond it, to listeners for the first time."


And elsewhere, CNN reports astronomers used the unique X-ray echoes released by rare "binary" black hole-star systems to identify six more such systems. (Only two were known previously.) And then converted their data into sound waves. The team tracked changes in the X-ray echoes, determined time lags during transition stages and traced commonalities in the evolution of each black hole outburst. The result sounds like something from a 1950s sci-fi film.

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